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    flp-4 FMRF-Like Peptide [ Caenorhabditis elegans ]

    Gene ID: 174568, updated on 9-Dec-2024

    Summary

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    Official Symbol
    flp-4
    Official Full Name
    FMRF-Like Peptide
    Primary source
    WormBase:WBGene00001447
    Locus tag
    CELE_C18D1.3
    See related
    AllianceGenome:WB:WBGene00001447
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in neuropeptide signaling pathway. Predicted to be located in extracellular region. Is expressed in nerve ring; pharyngeal neurons; and sensory neurons. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See flp-4 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    4
    Sequence:
    Chromosome: II; NC_003280.10 (10048868..10055561)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene SPK domain-containing protein Neighboring gene BTB and MATH domain-containing protein 38 Neighboring gene Uncharacterized protein Neighboring gene STarGazin (mammalian calcium channel) homolog Neighboring gene Major facilitator superfamily (MFS) profile domain-containing protein Neighboring gene C2H2-type domain-containing protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Expression and regulation of an FMRFamide-related neuropeptide gene family in Caenorhabditis elegans. Kim K, et al. J Comp Neurol, 2004 Aug 2. PMID 15236235
    2. FLP-4 neuropeptide and its receptor in a neuronal circuit regulate preference choice through functions of ASH-2 trithorax complex in Caenorhabditis elegans. Yu Y, et al. Sci Rep, 2016 Feb 18. PMID 26887501, Free PMC Article
    3. Changes in locomotory behavior and cAMP produced in Ascaris suum by neuropeptides from Ascaris suum or Caenorhabditis elegans. Reinitz CA, et al. Mol Biochem Parasitol, 2000 Nov. PMID 11087928
    4. FMRFamide-related peptides (FaRPs) in nematodes: occurrence and neuromuscular physiology. Maule AG, et al. Parasitology, 1996. PMID 9051931
    5. Improved statistical model checking methods for pathway analysis. Koh CH, et al. BMC Bioinformatics, 2012. PMID 23282174, Free PMC Article

    See all (23) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in neuropeptide signaling pathway IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    FMRF-Like Peptide
    NP_001379072.1
    • Product from WormBase gene class flp;
      Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      10048868..10055561
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001393175.1 → NP_001379072.1  FMRF-Like Peptide [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      G5EG31
    Nucleotide Protein
    Heading Accession and Version

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