syx-4 Putative syntaxin-4 [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: syx-4
Official Full Name: Putative syntaxin-4
Primary source: WormBase:WBGene00006374
Locus tag: CELE_T01B11.3
See related: AllianceGenome:WB:WBGene00006374
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable SNAP receptor activity and SNARE binding activity. Involved in cortical granule exocytosis; positive regulation of cytokinesis; and regulation of exocytosis. Located in cleavage furrow; cortical granule; and perinuclear region of cytoplasm. Is expressed in gonad and seam cell. [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See syx-4 in Genome Data Viewer

Location:: chromosome: IV

Exon count:: 5

Sequence:: Chromosome: IV; NC_003282.8 (8457280..8458933)

Chromosome IV - NC_003282.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003282.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

A Haemonchus contortus UNC-18 homologue binds to C. elegans neuronal syntaxin and may represent a neuronal UNC-18 isoform.
Title: Haemonchus contortus UNC-18 binds to Caenorhabditis elegans neuronal syntaxin.

Submit: New GeneRIF Correction

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

T01B11.3 (e-PCR)
- UniSTS:314832

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables SNAP receptor activity	IBA Inferred from Biological aspect of Ancestor more info
enables SNARE binding	IBA Inferred from Biological aspect of Ancestor more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed

Process	Evidence Code	Pubs
involved_in cortical granule exocytosis	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in exocytosis	IBA Inferred from Biological aspect of Ancestor more info
involved_in intracellular protein transport	IBA Inferred from Biological aspect of Ancestor more info
involved_in neurotransmitter transport	IEA Inferred from Electronic Annotation more info
involved_in positive regulation of cytokinesis	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in regulation of exocytosis	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in synaptic vesicle docking	ISS Inferred from Sequence or Structural Similarity more info
involved_in vesicle docking	IBA Inferred from Biological aspect of Ancestor more info
involved_in vesicle fusion	IBA Inferred from Biological aspect of Ancestor more info
involved_in vesicle-mediated transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of SNARE complex	IBA Inferred from Biological aspect of Ancestor more info
located_in cleavage furrow	IDA Inferred from Direct Assay more info	PubMed
located_in cortical granule	IDA Inferred from Direct Assay more info	PubMed
is_active_in endomembrane system	IBA Inferred from Biological aspect of Ancestor more info
located_in membrane	IEA Inferred from Electronic Annotation more info
located_in perinuclear region of cytoplasm	IDA Inferred from Direct Assay more info	PubMed
is_active_in plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in plasma membrane	IDA Inferred from Direct Assay more info	PubMed

General protein information

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Preferred Names: Putative syntaxin-4

NP_501439.2

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003282.8 Reference assembly

Range

8457280..8458933

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_069038.4 → NP_501439.2 Putative syntaxin-4 [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_501439.2

Status: REVIEWED

UniProtKB/Swiss-Prot

P91409

Conserved Domains (3) summary

smart00503
Location:31 → 142

SynN; Syntaxin N-terminal domain

cd15848
Location:194 → 254

SNARE_syntaxin1-like; SNARE motif of syntaxin 1 and related proteins

pfam00804
Location:33 → 228

Syntaxin; Syntaxin