hsp-43 SHSP domain-containing protein [Caenorhabditis elegans] - Gene

Summary

Go to the top of the page Help

Official Symbol: hsp-43
Official Full Name: SHSP domain-containing protein
Primary source: WormBase:WBGene00002024
Locus tag: CELE_C14F11.5
See related: AllianceGenome:WB:WBGene00002024
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable unfolded protein binding activity. Predicted to be involved in protein refolding and response to heat. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including copulatory spicule; hermaphrodite gonad; pharyngeal-intestinal valve; rectal valve cell; and vulva. [provided by Alliance of Genome Resources, Dec 2024]
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help

See hsp-43 in Genome Data Viewer

Location:: chromosome: X

Exon count:: 7

Sequence:: Chromosome: X; NC_003284.9 (6233151..6235543, complement)

Chromosome X - NC_003284.9 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:: NC_003284.9

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

Interactions

Go to the top of the page Help

Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

Go to the top of the page Help

Markers

C14F11.5 (e-PCR)
- UniSTS:309074

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables unfolded protein binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in protein refolding	IBA Inferred from Biological aspect of Ancestor more info
involved_in response to heat	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info

General protein information

Go to the top of the page Help

Preferred Names: SHSP domain-containing protein

NP_001123107.2

Confirmed by transcript evidence

NP_001379672.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003284.9 Reference assembly

Range

6233151..6235543 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001129635.6 → NP_001123107.2 SHSP domain-containing protein [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_001123107.2

Status: REVIEWED

UniProtKB/TrEMBL

B0M0L8

Conserved Domains (1) summary

cd06526
Location:107 → 186

metazoan_ACD; Alpha-crystallin domain (ACD) of metazoan alpha-crystallin-type small(s) heat shock proteins (Hsps). sHsps are small stress induced proteins with monomeric masses between 12 -43 kDa, whose common feature is the Alpha-crystallin domain (ACD). sHsps are ...
NM_001392785.1 → NP_001379672.1 SHSP domain-containing protein [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/TrEMBL

H2KYS1

Conserved Domains (1) summary

cd06526
Location:107 → 186

metazoan_ACD; Alpha-crystallin domain (ACD) of metazoan alpha-crystallin-type small(s) heat shock proteins (Hsps). sHsps are small stress induced proteins with monomeric masses between 12 -43 kDa, whose common feature is the Alpha-crystallin domain (ACD). sHsps are ...