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    acdh-4 Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial [ Caenorhabditis elegans ]

    Gene ID: 172367, updated on 9-Dec-2024

    Summary

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    Official Symbol
    acdh-4
    Official Full Name
    Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial
    Primary source
    WormBase:WBGene00020419
    Locus tag
    CELE_T10E9.9
    See related
    AllianceGenome:WB:WBGene00020419
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable acyl-CoA dehydrogenase activity. Predicted to be active in mitochondrion. Orthologous to human ACADSB (acyl-CoA dehydrogenase short/branched chain). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See acdh-4 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    6
    Sequence:
    Chromosome: I; NC_003279.8 (6546615..6548675, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene C2H2-type domain-containing protein Neighboring gene F-box domain-containing protein Neighboring gene ncRNA Neighboring gene Activator of basal transcription 1 Neighboring gene Inheritance of peroxisomes protein 1

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Comparative genomics and functional study of lipid metabolic genes in Caenorhabditis elegans. Zhang Y, et al. BMC Genomics, 2013 Mar 12. PMID 23496871, Free PMC Article
    2. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
    3. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    4. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables acyl-CoA dehydrogenase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables flavin adenine dinucleotide binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables oxidoreductase activity, acting on the CH-CH group of donors IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial
    NP_001300435.1
    • Confirmed by transcript evidence
    NP_491886.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      6546615..6548675 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_059485.5 → NP_491886.2  Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_491886.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      O01607
      Conserved Domains (2) summary
      COG1960
      Location:2 → 293
      CaiA; Acyl-CoA dehydrogenase related to the alkylation response protein AidB [Lipid transport and metabolism]
      cl09933
      Location:1 → 293
      ACAD; Acyl-CoA dehydrogenase

    2. NM_001313506.3 → NP_001300435.1  Short/branched chain specific acyl-CoA dehydrogenase, mitochondrial [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A0K3AQR2
      Conserved Domains (2) summary
      COG1960
      Location:41 → 359
      CaiA; Acyl-CoA dehydrogenase related to the alkylation response protein AidB [Lipid transport and metabolism]
      cl09933
      Location:43 → 359
      ACAD; Acyl-CoA dehydrogenase
    Nucleotide Protein
    Heading Accession and Version

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