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    C03C10.2 Putative casein kinase I C03C10.2 [ Caenorhabditis elegans ]

    Gene ID: 182156, updated on 2-Nov-2024

    Summary

    Official Symbol
    C03C10.2
    Official Full Name
    Putative casein kinase I C03C10.2
    Primary source
    WormBase:WBGene00007269
    Locus tag
    CELE_C03C10.2
    See related
    AllianceGenome:WB:WBGene00007269
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in signal transduction. Predicted to be active in cytoplasm and nucleus. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 11. Orthologous to human TTBK1 (tau tubulin kinase 1) and TTBK2 (tau tubulin kinase 2). [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

    See C03C10.2 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    4
    Sequence:
    Chromosome: III; NC_003281.10 (4091073..4093317)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Uncoordinated protein 79 Neighboring gene ncRNA Neighboring gene Casein kinase I isoform alpha Neighboring gene Uncharacterized protein Neighboring gene ncRNA Neighboring gene Ribonucleoside-diphosphate reductase small chain Neighboring gene Uncharacterized protein Neighboring gene Guanine nucleotide exchange factor rei-1 Neighboring gene ncRNA

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein serine kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein serine/threonine kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in protein phosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    Putative casein kinase I C03C10.2
    NP_497820.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      4091073..4093317
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_065419.4NP_497820.2  Putative casein kinase I C03C10.2 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_497820.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P42169
      Conserved Domains (2) summary
      pfam00069
      Location:50303
      Pkinase; Protein kinase domain
      cl21453
      Location:49317
      PKc_like; Protein Kinases, catalytic domain