ndub-7 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: ndub-7
Official Full Name: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7
Primary source: WormBase:WBGene00008414
Locus tag: CELE_D2030.4
See related: AllianceGenome:WB:WBGene00008414
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to be located in mitochondrial inner membrane and mitochondrial intermembrane space. Predicted to be part of respiratory chain complex I. Human ortholog(s) of this gene implicated in nuclear type mitochondrial complex I deficiency. Orthologous to human NDUFB7 (NADH:ubiquinone oxidoreductase subunit B7). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See ndub-7 in Genome Data Viewer

Location:: chromosome: I

Exon count:: 3

Sequence:: Chromosome: I; NC_003279.8 (7580944..7581628, complement)

Chromosome I - NC_003279.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003279.8

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

D2030.5 (e-PCR)
- UniSTS:316481

STS1-116 (e-PCR)
- UniSTS:241601

D2030.4 (e-PCR)
- UniSTS:320493

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Component	Evidence Code	Pubs
located_in mitochondrial inner membrane	IEA Inferred from Electronic Annotation more info
located_in mitochondrial intermembrane space	IEA Inferred from Electronic Annotation more info
located_in mitochondrion	IEA Inferred from Electronic Annotation more info
part_of respiratory chain complex	IEA Inferred from Electronic Annotation more info
part_of respiratory chain complex I	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7

NP_492119.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003279.8 Reference assembly

Range

7580944..7581628 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_059718.8 → NP_492119.1 NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 7 [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_492119.1

Status: REVIEWED

UniProtKB/Swiss-Prot

P90789

Conserved Domains (1) summary

pfam05676
Location:43 → 106

NDUF_B7; NADH-ubiquinone oxidoreductase B18 subunit (NDUFB7)