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    mog-7 GCF C-terminal domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 172662, updated on 9-Dec-2024

    Summary

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    Official Symbol
    mog-7
    Official Full Name
    GCF C-terminal domain-containing protein
    Primary source
    WormBase:WBGene00009672
    Locus tag
    CELE_F43G9.12
    See related
    AllianceGenome:WB:WBGene00009672
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable DNA binding activity. Predicted to be involved in spliceosomal complex disassembly. Predicted to be part of U2-type post-mRNA release spliceosomal complex. Predicted to be active in nucleus. Is expressed in germ cell; germline precursor cell; and somatic cell. Orthologous to human GCFC2 (GC-rich sequence DNA-binding factor 2) and PAXBP1 (PAX3 and PAX7 binding protein 1). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See mog-7 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    10
    Sequence:
    Chromosome: I; NC_003279.8 (8640508..8644399)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene C2H2-type domain-containing protein Neighboring gene Calponin-homology (CH) domain-containing protein Neighboring gene Microfibrillar-associated protein 1 Neighboring gene t-SNARE coiled-coil homology domain-containing protein Neighboring gene Peptidyl-prolyl cis-trans isomerase sig-7

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Functional recovery of the germ line following splicing collapse. Cao W, et al. Cell Death Differ, 2022 Apr. PMID 34663906, Free PMC Article
    2. Regulation of the C. elegans molt by pqn-47. Russel S, et al. Dev Biol, 2011 Dec 15. PMID 21989027, Free PMC Article
    3. Gene expression profiling of epidermal cell types in C. elegans using Targeted DamID. Katsanos D, et al. Development, 2021 Sep 1. PMID 34397094, Free PMC Article
    4. The Regulatory Landscape of Lineage Differentiation in a Metazoan Embryo. Du Z, et al. Dev Cell, 2015 Sep 14. PMID 26321128, Free PMC Article
    5. Defect-buffering cellular plasticity increases robustness of metazoan embryogenesis. Xiao L, et al. Cell Syst, 2022 Aug 17. PMID 35882226

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in mRNA splicing, via spliceosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in spliceosomal complex disassembly IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of U2-type post-mRNA release spliceosomal complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    GCF C-terminal domain-containing protein
    NP_001250839.1
    • Confirmed by transcript evidence
    NP_001250840.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      8640508..8644399
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001263910.2 → NP_001250839.1  GCF C-terminal domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001250839.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      G5ECH1
      Conserved Domains (1) summary
      pfam07842
      Location:537 → 671
      GCFC; GC-rich sequence DNA-binding factor-like protein

    2. NM_001263911.3 → NP_001250840.1  GCF C-terminal domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001250840.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      G5EBK6
      Conserved Domains (1) summary
      pfam07842
      Location:37 → 171
      GCFC; GC-rich sequence DNA-binding factor-like protein
    Nucleotide Protein
    Heading Accession and Version

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