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    lron-7 LRRCT domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 180991, updated on 9-Dec-2024

    Summary

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    Official Symbol
    lron-7
    Official Full Name
    LRRCT domain-containing protein
    Primary source
    WormBase:WBGene00019351
    Locus tag
    CELE_K03A1.2
    See related
    AllianceGenome:WB:WBGene00019351
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable chromatin binding activity. Predicted to be involved in chromatin organization and establishment of protein localization to chromatin. Predicted to be located in several cellular components, including centrosome; cytoplasm; and nucleus. Predicted to be part of nuclear origin of replication recognition complex. Is expressed in head and intestine. Orthologous to human OPTC (opticin). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See lron-7 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    13
    Sequence:
    Chromosome: X; NC_003284.9 (7292132..7296040)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene Rab-3-interacting molecule unc-10 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene EF-hand domain-containing protein Neighboring gene ncRNA Neighboring gene Acetoacetyl-CoA synthetase

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Function of cell adhesion molecules in differentiation of ray sensory neurons in C. elegans. Sakai N, et al. G3 (Bethesda), 2023 Mar 9. PMID 36573343, Free PMC Article
    2. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables chromatin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in cell development IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in chromatin organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in establishment of protein localization to chromatin IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    located_in centrosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of nuclear origin of replication recognition complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    LRRCT domain-containing protein
    NP_001123160.1
    • Confirmed by transcript evidence
    NP_001360787.1
    • Confirmed by transcript evidence
    NP_509227.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      7292132..7296040
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001129688.5 → NP_001123160.1  LRRCT domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001123160.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      H2L0D5
      Conserved Domains (3) summary
      smart00082
      Location:463 → 510
      LRRCT; Leucine rich repeat C-terminal domain
      COG4886
      Location:204 → 417
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      sd00033
      Location:206 → 229
      LRR_RI; leucine-rich repeat [structural motif]

    2. NM_001373353.1 → NP_001360787.1  LRRCT domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A4V0IJI7
      Conserved Domains (3) summary
      smart00082
      Location:510 → 557
      LRRCT; Leucine rich repeat C-terminal domain
      COG4886
      Location:251 → 464
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      sd00033
      Location:253 → 276
      LRR_RI; leucine-rich repeat [structural motif]

    3. NM_076826.9 → NP_509227.2  LRRCT domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_509227.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q21164
      Conserved Domains (3) summary
      smart00082
      Location:463 → 510
      LRRCT; Leucine rich repeat C-terminal domain
      COG4886
      Location:204 → 417
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      sd00033
      Location:206 → 229
      LRR_RI; leucine-rich repeat [structural motif]
    Nucleotide Protein
    Heading Accession and Version

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