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    gur-3 Gustatory receptor family protein 3 [ Caenorhabditis elegans ]

    Gene ID: 181245, updated on 9-Dec-2024

    Summary

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    Official Symbol
    gur-3
    Official Full Name
    Gustatory receptor family protein 3
    Primary source
    WormBase:WBGene00001804
    Locus tag
    CELE_ZC504.5
    See related
    AllianceGenome:WB:WBGene00001804
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in sensory perception of taste. Located in nucleus. Is expressed in AVDL; AVDR; I2L; I2R; and I4 neuron. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See gur-3 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    12
    Sequence:
    Chromosome: X; NC_003284.9 (10402522..10406303, complement)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene protein kinase C Neighboring gene ncRNA Neighboring gene BPTI/Kunitz inhibitor domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. TWISP: a transgenic worm for interrogating signal propagation in Caenorhabditis elegans. Sharma AK, et al. Genetics, 2024 Jul 8. PMID 38733622, Free PMC Article
    2. Light evokes stereotyped global brain dynamics in Caenorhabditis elegans. Gauthey W, et al. Curr Biol, 2024 Jan 8. PMID 38194919,
    3. Structure-function analysis suggests that the photoreceptor LITE-1 is a light-activated ion channel. Hanson SM, et al. Curr Biol, 2023 Aug 21. PMID 37527662
    4. Light and hydrogen peroxide inhibit C. elegans Feeding through gustatory receptor orthologs and pharyngeal neurons. Bhatla N, et al. Neuron, 2015 Feb 18. PMID 25640076, Free PMC Article
    5. Neural signal propagation atlas of Caenorhabditis elegans. Randi F, et al. Nature, 2023 Nov. PMID 37914938, Free PMC Article

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. This study demonistrated that the gustatory receptor family members LITE-1 and GUR-3 are required for the inhibition of feeding by light and hydrogen peroxide
      Title: Light and hydrogen peroxide inhibit C. elegans Feeding through gustatory receptor orthologs and pharyngeal neurons.
    Submit: New GeneRIF Correction

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in sensory perception of taste IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in axon IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in dendrite IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in neuronal cell body IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    Gustatory receptor family protein 3
    NP_509743.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      10402522..10406303 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_077342.6 → NP_509743.2  Gustatory receptor family protein 3 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_509743.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      O18280, Q963E7
      Conserved Domains (1) summary
      pfam08395
      Location:46 → 425
      7tm_7; 7tm Chemosensory receptor
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    O18280.3

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