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    dmd-9 DM domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 190512, updated on 9-Dec-2024

    Summary

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    Official Symbol
    dmd-9
    Official Full Name
    DM domain-containing protein
    Primary source
    WormBase:WBGene00022060
    Locus tag
    CELE_Y67D8A.3
    See related
    AllianceGenome:WB:WBGene00022060
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II and sex differentiation. Predicted to be active in nucleus. Is expressed in several structures, including BAG; amphid neurons; somatic nervous system; sperm; and tail. Orthologous to human DMRTB1 (DMRT like family B with proline rich C-terminal 1); DMRTC1 (DMRT like family C1); and DMRTC1B (DMRT like family C1B). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See dmd-9 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    4
    Sequence:
    Chromosome: IV; NC_003282.8 (3253261..3254543, complement)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene Phosphorylase b kinase regulatory subunit Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Characterization of the Doublesex/MAB-3 transcription factor DMD-9 in Caenorhabditis elegans. Godini R, et al. G3 (Bethesda), 2023 Feb 9. PMID 36454093, Free PMC Article
    2. Extensive rewiring and complex evolutionary dynamics in a C. elegans multiparameter transcription factor network. Reece-Hoyes JS, et al. Mol Cell, 2013 Jul 11. PMID 23791784, Free PMC Article
    3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Characterization of the Doublesex/MAB-3 transcription factor DMD-9 in Caenorhabditis elegans.
      Title: Characterization of the Doublesex/MAB-3 transcription factor DMD-9 in Caenorhabditis elegans.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in sex differentiation IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    DM domain-containing protein
    NP_500305.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      3253261..3254543 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_067904.4 → NP_500305.1  DM domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_500305.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q95XU1
      Conserved Domains (1) summary
      smart00301
      Location:27 → 79
      DM; Doublesex DNA-binding motif
    Nucleotide Protein
    Heading Accession and Version

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