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    mrpl-45 Large ribosomal subunit protein mL45 [ Caenorhabditis elegans ]

    Gene ID: 191044, updated on 4-Jan-2025

    Summary

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    Official Symbol
    mrpl-45
    Official Full Name
    Large ribosomal subunit protein mL45
    Primary source
    WormBase:WBGene00022493
    Locus tag
    CELE_Y119D3B.16
    See related
    AllianceGenome:WB:WBGene00022493
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be located in ribosome. Predicted to be part of ribonucleoprotein complex. Predicted to be active in mitochondrion. Orthologous to human MRPL45 (mitochondrial ribosomal protein L45). [provided by Alliance of Genome Resources, Jan 2025]
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    Genomic context

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    See mrpl-45 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    5
    Sequence:
    Chromosome: III; NC_003281.10 (1196389..1202008, complement)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Tr-type G domain-containing protein Neighboring gene putative 26S proteasome complex subunit dss-1 Neighboring gene LUC7 related splicing factor homolog;Luc7-like protein 3 Neighboring gene ORC_WH_C domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The RNA-binding protein repertoire of Arabidopsis thaliana. Marondedze C, et al. Sci Rep, 2016 Jul 11. PMID 27405932, Free PMC Article
    2. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
    3. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    4. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Component Evidence Code Pubs
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Large ribosomal subunit protein mL45
    NP_497347.3
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      1196389..1202008 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_064946.8 → NP_497347.3  Large ribosomal subunit protein mL45 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_497347.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q95Y71
      Conserved Domains (1) summary
      smart00978
      Location:156 → 304
      Tim44; Tim44 is an essential component of the machinery that mediates the translocation of nuclear-encoded proteins across the mitochondrial inner membrane
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q95Y71.3

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