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    F35B3.7 Leucine-rich repeat-containing protein DDB_G0290503 [ Caenorhabditis elegans ]

    Gene ID: 185257, updated on 9-Dec-2024

    Summary

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    Official Symbol
    F35B3.7
    Official Full Name
    Leucine-rich repeat-containing protein DDB_G0290503
    Primary source
    WormBase:WBGene00018033
    Locus tag
    CELE_F35B3.7
    See related
    AllianceGenome:WB:WBGene00018033
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be located in cytoplasm. Human ortholog(s) of this gene implicated in breast carcinoma; esophageal cancer; esophagus squamous cell carcinoma; and squamous cell carcinoma. Orthologous to human LZTS1 (leucine zipper tumor suppressor 1) and LZTS2 (leucine zipper tumor suppressor 2). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See F35B3.7 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    16
    Sequence:
    Chromosome: X; NC_003284.9 (17035194..17043078, complement)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene protein of unknown function DB domain-containing protein Neighboring gene Patronin (microtubule-binding protein) homolog Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene BTB domain-containing protein Neighboring gene Receptor-type guanylate cyclase gcy-11

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. SH3 interactome conserves general function over specific form. Xin X, et al. Mol Syst Biol, 2013. PMID 23549480, Free PMC Article
    2. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
    3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Leucine-rich repeat-containing protein DDB_G0290503
    NP_510753.3
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      17035194..17043078 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_078352.8 → NP_510753.3  Leucine-rich repeat-containing protein DDB_G0290503 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_510753.3

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q966J7
      Conserved Domains (1) summary
      TIGR02168
      Location:423 → 565
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    Nucleotide Protein
    Heading Accession and Version

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