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    clec-70 C-type lectin domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 189944, updated on 9-Dec-2024

    Summary

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    Official Symbol
    clec-70
    Official Full Name
    C-type lectin domain-containing protein
    Primary source
    WormBase:WBGene00021581
    Locus tag
    CELE_Y46C8AL.3
    See related
    AllianceGenome:WB:WBGene00021581
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Involved in defense response to Gram-positive bacterium. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See clec-70 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    9
    Sequence:
    Chromosome: IV; NC_003282.8 (3932708..3936307)

    Chromosome IV - NC_003282.8Genomic Context describing neighboring genes Neighboring gene C-type lectin domain-containing protein Neighboring gene pseudo Neighboring gene C-type lectin domain-containing protein Neighboring gene C-type lectin domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003282.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Uptake of TiO(2) Nanoparticles into C. elegans Neurons Negatively Affects Axonal Growth and Worm Locomotion Behavior. Hu CC, et al. ACS Appl Mater Interfaces, 2018 Mar 14. PMID 29464946
    2. Caenorhabditis elegans mounts a p38 MAPK pathway-mediated defence to Cutibacterium acnes infection. Huang X, et al. Cell Microbiol, 2020 Oct. PMID 32543022
    3. Distinct pathogenesis and host responses during infection of C. elegans by P. aeruginosa and S. aureus. Irazoqui JE, et al. PLoS Pathog, 2010 Jul 1. PMID 20617181, Free PMC Article
    4. The transcriptional coactivator CBP/p300 is an evolutionarily conserved node that promotes longevity in response to mitochondrial stress. Li TY, et al. Nat Aging, 2021 Feb. PMID 33718883, Free PMC Article
    5. Specificity of the innate immune system and diversity of C-type lectin domain (CTLD) proteins in the nematode Caenorhabditis elegans. Schulenburg H, et al. Immunobiology, 2008. PMID 18406370

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in defense response to Gram-positive bacterium IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    C-type lectin domain-containing protein
    NP_500439.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003282.8 Reference assembly

      Range
      3932708..3936307
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_068038.4 → NP_500439.2  C-type lectin domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_500439.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9N3X0
      Conserved Domains (1) summary
      smart00034
      Location:20 → 145
      CLECT; C-type lectin (CTL) or carbohydrate-recognition domain (CRD)
    Nucleotide Protein
    Heading Accession and Version

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