U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    F32D1.3 TPR_REGION domain-containing protein;dolichyl-phosphate-mannose--protein mannosyltransferase [ Caenorhabditis elegans ]

    Gene ID: 178832, updated on 9-Dec-2024

    Summary

    Official Symbol
    F32D1.3
    Official Full Name
    TPR_REGION domain-containing protein;dolichyl-phosphate-mannose--protein mannosyltransferase
    Primary source
    WormBase:WBGene00017983
    Locus tag
    CELE_F32D1.3
    See related
    AllianceGenome:WB:WBGene00017983
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable mannosyltransferase activity. Predicted to be involved in protein O-linked mannosylation. Predicted to be located in endoplasmic reticulum and membrane. Predicted to be active in endoplasmic reticulum membrane. Orthologous to human TMTC2 (transmembrane O-mannosyltransferase targeting cadherins 2). [provided by Alliance of Genome Resources, Dec 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See F32D1.3 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    8
    Sequence:
    Chromosome: V; NC_003283.11 (4349751..4361569, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene AAA domain-containing protein;Fidgetin-like protein 1;Spastin/Vps4 C-terminal domain-containing protein Neighboring gene ATP synthase subunit epsilon, mitochondrial Neighboring gene DNA replication licensing factor MCM7 Neighboring gene ncRNA Neighboring gene Ground-like domain-containing protein Neighboring gene Activin_recp domain-containing protein

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables dolichyl-phosphate-mannose-protein mannosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables glycosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables mannosyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in protein O-linked mannosylation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in protein glycosylation IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    TPR_REGION domain-containing protein;dolichyl-phosphate-mannose--protein mannosyltransferase
    NP_001317807.1
    • Confirmed by transcript evidence
    NP_504200.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      4349751..4361569 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_071799.5NP_504200.1  dolichyl-phosphate-mannose--protein mannosyltransferase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_504200.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O16296
      Conserved Domains (3) summary
      COG0457
      Location:448748
      TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
      sd00006
      Location:655681
      TPR; TPR repeat [structural motif]
      pfam08409
      Location:244316
      DUF1736; Domain of unknown function (DUF1736)
    2. NM_001330857.3NP_001317807.1  TPR_REGION domain-containing protein [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/TrEMBL
      A0A168H4S5
      Conserved Domains (1) summary
      sd00006
      Location:737
      TPR; TPR repeat [structural motif]

    RNA

    1. NR_138492.1 RNA Sequence

      Status: REVIEWED