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    ins-31 INSulin related [ Caenorhabditis elegans ]

    Gene ID: 173660, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ins-31
    Official Full Name
    INSulin related
    Primary source
    WormBase:WBGene00002114
    Locus tag
    CELE_T10D4.4
    See related
    AllianceGenome:WB:WBGene00002114
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable hormone activity. Predicted to be involved in signal transduction. Predicted to be located in extracellular region. Is expressed in coelomocyte and male gonad. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See ins-31 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    3
    Sequence:
    Chromosome: II; NC_003280.10 (3127041..3127831)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Serpentine Receptor, class H Neighboring gene INSulin related Neighboring gene GH18 domain-containing protein Neighboring gene pseudo

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. GABAergic synapses suppress intestinal innate immunity via insulin signaling in Caenorhabditis elegans. Zheng Z, et al. Proc Natl Acad Sci U S A, 2021 May 18. PMID 33972423, Free PMC Article
    2. Intestine-to-neuronal signaling alters risk-taking behaviors in food-deprived Caenorhabditis elegans. Matty MA, et al. PLoS Genet, 2022 May. PMID 35511794, Free PMC Article
    3. Males shorten the life span of C. elegans hermaphrodites via secreted compounds. Maures TJ, et al. Science, 2014 Jan 31. PMID 24292626, Free PMC Article
    4. Insulin worms its way into the spotlight. Nelson DW, et al. Genes Dev, 2003 Apr 1. PMID 12670864
    5. Genome-wide analysis of sex-enriched gene expression during C. elegans larval development. Thoemke K, et al. Dev Biol, 2005 Aug 15. PMID 15987632

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables hormone activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in signal transduction IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    INSulin related
    NP_494454.1
    • Product from WormBase gene class ins;
      Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      3127041..3127831
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_062053.3 → NP_494454.1  INSulin related [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_494454.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9TZF3
      Conserved Domains (1) summary
      pfam03488
      Location:93 → 142
      Ins_beta; Nematode insulin-related peptide beta type
    Nucleotide Protein
    Heading Accession and Version

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