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    pup-3 PAP-associated domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 172207, updated on 2-Nov-2024

    Summary

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    Official Symbol
    pup-3
    Official Full Name
    PAP-associated domain-containing protein
    Primary source
    WormBase:WBGene00019082
    Locus tag
    CELE_F59A3.9
    See related
    AllianceGenome:WB:WBGene00019082
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable poly(A) RNA polymerase activity. Predicted to be involved in RNA 3'-end processing. [provided by Alliance of Genome Resources, Nov 2024]
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    Genomic context

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    See pup-3 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    8
    Sequence:
    Chromosome: I; NC_003279.8 (5530616..5534649, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene ncRNA Neighboring gene Carboxypeptidase D Neighboring gene Tyrosine-protein kinase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Lethal giant larvae homologue 2 domain-containing protein;V-SNARE coiled-coil homology domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. The balance of poly(U) polymerase activity ensures germline identity, survival and development in Caenorhabditis elegans. Li Y, et al. Development, 2018 Oct 10. PMID 30305273, Free PMC Article
    2. A family of poly(U) polymerases. Kwak JE, et al. RNA, 2007 Jun. PMID 17449726, Free PMC Article
    3. LIN-28 and the poly(U) polymerase PUP-2 regulate let-7 microRNA processing in Caenorhabditis elegans. Lehrbach NJ, et al. Nat Struct Mol Biol, 2009 Oct. PMID 19713957, Free PMC Article
    4. Screening by deep sequencing reveals mediators of microRNA tailing in C. elegans. Vieux KF, et al. Nucleic Acids Res, 2021 Nov 8. PMID 34586415, Free PMC Article
    5. Predicting PDZ domain-peptide interactions from primary sequences. Chen JR, et al. Nat Biotechnol, 2008 Sep. PMID 18711339, Free PMC Article

    See all (8) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables poly(A) RNA polymerase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in RNA 3'-end processing IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    PAP-associated domain-containing protein
    NP_491621.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      5530616..5534649 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_059220.5 → NP_491621.1  PAP-associated domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_491621.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      P91361
      Conserved Domains (1) summary
      COG5260
      Location:90 → 374
      TRF4; DNA polymerase sigma [Replication, recombination and repair]
    Nucleotide Protein
    Heading Accession and Version

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