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    bmy-1 Boca/MESD chaperone for YWTD beta-propeller-EGF [ Caenorhabditis elegans ]

    Gene ID: 173908, updated on 9-Dec-2024

    Summary

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    Official Symbol
    bmy-1
    Official Full Name
    Boca/MESD chaperone for YWTD beta-propeller-EGF
    Primary source
    WormBase:WBGene00017293
    Locus tag
    CELE_F09E5.17
    See related
    AllianceGenome:WB:WBGene00017293
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Enables identical protein binding activity. Predicted to be involved in protein folding. Predicted to be located in endoplasmic reticulum. Human ortholog(s) of this gene implicated in osteogenesis imperfecta type 20. Orthologous to human MESD (mesoderm development LRP chaperone). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See bmy-1 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    3
    Sequence:
    Chromosome: II; NC_003280.10 (5358695..5359469)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Serpentine receptor class gamma-69 Neighboring gene Transmembrane protein 199 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Exocyst complex component 3 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene U-scoloptoxin(04)-

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Structural characterization of the Boca/Mesd maturation factors for LDL-receptor-type β propeller domains. Collins MN, et al. Structure, 2011 Mar 9. PMID 21397184, Free PMC Article
    2. Ca(2+)/Calmodulin-binding proteins from the C. elegans proteome. Shen X, et al. Cell Calcium, 2008 May. PMID 17854888
    3. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    4. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables identical protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in protein folding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Boca/MESD chaperone for YWTD beta-propeller-EGF
    NP_495003.2
    • Product from WormBase gene class bmy;
      Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      5358695..5359469
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_062602.3 → NP_495003.2  Boca/MESD chaperone for YWTD beta-propeller-EGF [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_495003.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8IG33
      Conserved Domains (1) summary
      pfam10185
      Location:24 → 186
      Mesd; Chaperone for wingless signalling and trafficking of LDL receptor
    Nucleotide Protein
    Heading Accession and Version

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