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    mtss-1 Single-stranded DNA-binding protein, mitochondrial [ Caenorhabditis elegans ]

    Gene ID: 187502, updated on 27-Dec-2024

    Summary

    Official Symbol
    mtss-1
    Official Full Name
    Single-stranded DNA-binding protein, mitochondrial
    Primary source
    WormBase:WBGene00019800
    Locus tag
    CELE_PAR2.1
    See related
    AllianceGenome:WB:WBGene00019800
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable enzyme activator activity and single-stranded DNA binding activity. Predicted to be involved in DNA unwinding involved in DNA replication; mitochondrial genome maintenance; and positive regulation of mitochondrial DNA replication. Predicted to be located in mitochondrion. Predicted to be active in mitochondrial nucleoid. Is expressed in several structures, including body wall musculature; head; intestine; pharynx; and tail. Human ortholog(s) of this gene implicated in optic atrophy. Orthologous to human SSBP1 (single stranded DNA binding protein 1). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See mtss-1 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    3
    Sequence:
    Chromosome: III; NC_003281.10 (8768311..8769255)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Dwarfin sma-2;MH2 domain-containing protein Neighboring gene 5'-AMP-activated protein kinase catalytic subunit alpha-1 Neighboring gene Chondroitin sulfate synthase mig-22 Neighboring gene Glycerol-3-phosphate phosphatase;Putative NipSnap protein K02D10.1 Neighboring gene Uncharacterized protein Neighboring gene Uncharacterized protein

    Genomic regions, transcripts, and products

    Genomic Sequence:
    NC_003281.10

    Interactions

    General gene information

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables DNA binding  
    enables enzyme activator activity  
    enables protein binding PubMed 
    enables single-stranded DNA binding  
    enables single-stranded DNA binding  
    Process Evidence Code Pubs
    involved_in DNA replication  
    involved_in DNA unwinding involved in DNA replication  
    involved_in mitochondrial genome maintenance  
    involved_in positive regulation of mitochondrial DNA replication  
    Component Evidence Code Pubs
    is_active_in mitochondrial nucleoid  
    located_in mitochondrial nucleoid  
    located_in mitochondrion  

    General protein information

    Preferred Names
    Single-stranded DNA-binding protein, mitochondrial
    NP_498935.1
    • Partially confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      8768311..8769255
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_066534.5 → NP_498935.1  Single-stranded DNA-binding protein, mitochondrial [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_498935.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P34496
      Conserved Domains (2) summary
      COG0629
      Location:53 → 170
      Ssb; Single-stranded DNA-binding protein [Replication, recombination and repair]
      pfam00436
      Location:54 → 159
      SSB; Single-strand binding protein family
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