hpr-9 Cell cycle checkpoint control protein;Cell cycle checkpoint protein hpr-9 [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: hpr-9
Official Full Name: Cell cycle checkpoint control protein;Cell cycle checkpoint protein hpr-9
Primary source: WormBase:WBGene00001997
Locus tag: CELE_Y39A1A.23
See related: AllianceGenome:WB:WBGene00001997
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to be involved in DNA integrity checkpoint signaling; DNA repair; and cellular response to ionizing radiation. Predicted to be located in nucleus. Predicted to be part of checkpoint clamp complex. Orthologous to several human genes including RAD9B (RAD9 checkpoint clamp component B). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See hpr-9 in Genome Data Viewer

Location:: chromosome: III

Exon count:: 12

Sequence:: Chromosome: III; NC_003281.10 (10621551..10626398)

Chromosome III - NC_003281.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

STS3-189 (e-PCR)
- UniSTS:242033

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Process	Evidence Code	Pubs
involved_in DNA damage checkpoint signaling	IEA Inferred from Electronic Annotation more info
involved_in DNA repair	IBA Inferred from Biological aspect of Ancestor more info
involved_in DNA replication checkpoint signaling	IBA Inferred from Biological aspect of Ancestor more info
involved_in cellular response to ionizing radiation	IBA Inferred from Biological aspect of Ancestor more info
involved_in mitotic intra-S DNA damage checkpoint signaling	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
part_of checkpoint clamp complex	IBA Inferred from Biological aspect of Ancestor more info
part_of checkpoint clamp complex	IEA Inferred from Electronic Annotation more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: Cell cycle checkpoint control protein;Cell cycle checkpoint protein hpr-9

NP_001368495.1

Confirmed by transcript evidence

NP_499342.3

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003281.10 Reference assembly

Range

10621551..10626398

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_066941.7 → NP_499342.3 Cell cycle checkpoint protein hpr-9 [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/Swiss-Prot

Q95Q27

Conserved Domains (1) summary

pfam04139
Location:40 → 299

Rad9; Rad9
NM_001379907.1 → NP_001368495.1 Cell cycle checkpoint control protein [Caenorhabditis elegans]

Status: REVIEWED

UniProtKB/TrEMBL

A0A1W7LFZ8

Conserved Domains (1) summary

pfam04139
Location:16 → 275

Rad9