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    cyk-7 Cytokinesis defective protein 7 [ Caenorhabditis elegans ]

    Gene ID: 176092, updated on 9-Dec-2024

    Summary

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    Official Symbol
    cyk-7
    Official Full Name
    Cytokinesis defective protein 7
    Primary source
    WormBase:WBGene00015591
    Locus tag
    CELE_C08C3.4
    See related
    AllianceGenome:WB:WBGene00015591
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Involved in intercellular bridge organization. Located in Flemming body. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See cyk-7 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    6
    Sequence:
    Chromosome: III; NC_003281.10 (7793446..7795409, complement)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene BTB and MATH domain-containing protein 15;BTB domain-containing protein Neighboring gene Homeobox protein mab-5 Neighboring gene ncRNA Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Actomyosin contractility regulators stabilize the cytoplasmic bridge between the two primordial germ cells during Caenorhabditis elegans embryogenesis. Goupil E, et al. Mol Biol Cell, 2017 Dec 15. PMID 29074566, Free PMC Article
    2. The initial expansion of the C. elegans syncytial germ line is coupled to incomplete primordial germ cell cytokinesis. Bauer J, et al. Development, 2021 Sep 15. PMID 34195824, Free PMC Article
    3. A unified mode of epigenetic gene silencing: RNA meets polycomb group proteins. Sun Y, et al. RNA Biol, 2005 Jan. PMID 17132931
    4. The midbody ring scaffolds the abscission machinery in the absence of midbody microtubules. Green RA, et al. J Cell Biol, 2013 Nov 11. PMID 24217623, Free PMC Article
    5. A high-resolution C. elegans essential gene network based on phenotypic profiling of a complex tissue. Green RA, et al. Cell, 2011 Apr 29. PMID 21529718, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in intercellular bridge organization IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in Flemming body IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Cytokinesis defective protein 7
    NP_001040845.2
    • Partially confirmed by transcript evidence
    NP_001040846.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      7793446..7795409 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001047380.5 → NP_001040845.2  Cytokinesis defective protein 7 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001040845.2

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      A8WFF0, A8WFF1, P34325
      Conserved Domains (2) summary
      smart00225
      Location:45 → 137
      BTB; Broad-Complex, Tramtrack and Bric a brac
      cl02518
      Location:45 → 134
      BTB; BTB/POZ domain

    2. NM_001047381.3 → NP_001040846.1  Cytokinesis defective protein 7 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001040846.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P34325
      Conserved Domains (2) summary
      smart00225
      Location:31 → 123
      BTB; Broad-Complex, Tramtrack and Bric a brac
      cl02518
      Location:31 → 120
      BTB; BTB/POZ domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P34325.2

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