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    prel-3 PRELI/MSF1 domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 173040, updated on 9-Dec-2024

    Summary

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    Official Symbol
    prel-3
    Official Full Name
    PRELI/MSF1 domain-containing protein
    Primary source
    WormBase:WBGene00008856
    Locus tag
    CELE_F15D3.6
    See related
    AllianceGenome:WB:WBGene00008856
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable phosphatidic acid transfer activity. Predicted to be involved in phospholipid transport. Predicted to be active in mitochondrial intermembrane space. Orthologous to several human genes including PRELID3B (PRELI domain containing 3B). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See prel-3 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    6
    Sequence:
    Chromosome: I; NC_003279.8 (11572093..11577488, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene SERPIN domain-containing protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Uncharacterized protein Neighboring gene Mitochondrial import inner membrane translocase subunit TIM23 Neighboring gene tRNA-Lys

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Defect-buffering cellular plasticity increases robustness of metazoan embryogenesis. Xiao L, et al. Cell Syst, 2022 Aug 17. PMID 35882226
    2. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    3. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables phosphatidic acid transfer activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in intermembrane lipid transfer IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in phospholipid transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in mitochondrial intermembrane space IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrial intermembrane space IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    PRELI/MSF1 domain-containing protein
    NP_492952.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      11572093..11577488 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_060551.6 → NP_492952.1  PRELI/MSF1 domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_492952.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O62173
      Conserved Domains (1) summary
      pfam04707
      Location:15 → 168
      PRELI; PRELI-like family
    Nucleotide Protein
    Heading Accession and Version

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