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    yif-1 Protein YIF1 [ Caenorhabditis elegans ]

    Gene ID: 179400, updated on 9-Dec-2024

    Summary

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    Official Symbol
    yif-1
    Official Full Name
    Protein YIF1
    Primary source
    WormBase:WBGene00010178
    Locus tag
    CELE_F57A8.2
    See related
    AllianceGenome:WB:WBGene00010178
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in endoplasmic reticulum to Golgi vesicle-mediated transport. Predicted to be located in Golgi apparatus; endoplasmic reticulum; and membrane. Predicted to be active in several cellular components, including COPII-coated ER to Golgi transport vesicle; Golgi membrane; and endoplasmic reticulum-Golgi intermediate compartment. Is expressed in linker cell. Used to study Parkinson's disease. Orthologous to several human genes including YIF1A (Yip1 interacting factor homolog A, membrane trafficking protein). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See yif-1 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    8
    Sequence:
    Chromosome: V; NC_003283.11 (10050047..10054913, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Protein TSSC4 Neighboring gene Uncharacterized protein Neighboring gene ncRNA Neighboring gene Seven TM Receptor Neighboring gene FIP (Fungus-Induced Protein) Related Neighboring gene G-protein coupled receptors family 1 profile domain-containing protein Neighboring gene Nuclear receptor domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Antagonistic fungal enterotoxins intersect at multiple levels with host innate immune defences. Zhang X, et al. PLoS Genet, 2021 Jun. PMID 34166401, Free PMC Article
    2. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
    3. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    4. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    5. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in endoplasmic reticulum to Golgi vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in protein transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in COPII-coated ER to Golgi transport vesicle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in Golgi membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in Golgi membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in endoplasmic reticulum-Golgi intermediate compartment IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in endoplasmic reticulum-Golgi intermediate compartment IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Protein YIF1
    NP_001041126.1
    • Confirmed by transcript evidence
    NP_001041127.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      10050047..10054913 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001047662.4 → NP_001041127.1  Protein YIF1 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001041127.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q2PJ77
      Conserved Domains (1) summary
      pfam03878
      Location:103 → 323
      YIF1; YIF1

    2. NM_001047661.5 → NP_001041126.1  Protein YIF1 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001041126.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q20913
      Conserved Domains (1) summary
      pfam03878
      Location:103 → 323
      YIF1; YIF1
    Nucleotide Protein
    Heading Accession and Version

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