cept-2 Choline/EthanolaminePhosphoTransferase [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: cept-2
Official Full Name: Choline/EthanolaminePhosphoTransferase
Primary source: WormBase:WBGene00013024
Locus tag: CELE_Y49A3A.1
See related: AllianceGenome:WB:WBGene00013024
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable diacylglycerol cholinephosphotransferase activity and ethanolaminephosphotransferase activity. Predicted to be involved in phosphatidylethanolamine biosynthetic process. Predicted to be located in membrane. Predicted to be active in Golgi apparatus and endoplasmic reticulum membrane. Orthologous to several human genes including CHPT1 (choline phosphotransferase 1). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See cept-2 in Genome Data Viewer

Location:: chromosome: V

Exon count:: 5

Sequence:: Chromosome: V; NC_003283.11 (14347766..14351482)

Chromosome V - NC_003283.11 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003283.11

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

Y49A3A.1 (e-PCR)
- UniSTS:317315

F47B8.11 (e-PCR)
- UniSTS:315836

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables diacylglycerol cholinephosphotransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables ethanolaminephosphotransferase activity	IBA Inferred from Biological aspect of Ancestor more info
enables phosphotransferase activity, for other substituted phosphate groups	IEA Inferred from Electronic Annotation more info
enables transferase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in CDP-choline pathway	IEA Inferred from Electronic Annotation more info
involved_in phosphatidylethanolamine biosynthetic process	IBA Inferred from Biological aspect of Ancestor more info
involved_in phospholipid biosynthetic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
is_active_in Golgi apparatus	IBA Inferred from Biological aspect of Ancestor more info
is_active_in endoplasmic reticulum membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: Choline/EthanolaminePhosphoTransferase

NP_506558.2

Product from WormBase gene class cept;
Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003283.11 Reference assembly

Range

14347766..14351482

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_074157.7 → NP_506558.2 Choline/EthanolaminePhosphoTransferase [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_506558.2

Status: REVIEWED

UniProtKB/TrEMBL

G5EC25

Conserved Domains (1) summary

cl00453
Location:53 → 421

CDP-OH_P_transf; CDP-alcohol phosphatidyltransferase