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    mppe-1 Metallophosphoesterase 1 homolog [ Caenorhabditis elegans ]

    Gene ID: 172956, updated on 9-Dec-2024

    Summary

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    Official Symbol
    mppe-1
    Official Full Name
    Metallophosphoesterase 1 homolog
    Primary source
    WormBase:WBGene00015238
    Locus tag
    CELE_B0511.13
    See related
    AllianceGenome:WB:WBGene00015238
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable hydrolase activity and metal ion binding activity. Predicted to be involved in GPI anchor biosynthetic process and vesicle-mediated transport. Predicted to be located in Golgi apparatus and endoplasmic reticulum-Golgi intermediate compartment membrane. Orthologous to human MPPE1 (metallophosphoesterase 1). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See mppe-1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    5
    Sequence:
    Chromosome: I; NC_003279.8 (10634568..10636028, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene FHA domain-containing protein Neighboring gene Uncharacterized protein Neighboring gene ncRNA Neighboring gene Mitochondrial Ribosomal Protein, Small

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification of genes that protect the C. elegans genome against mutations by genome-wide RNAi. Pothof J, et al. Genes Dev, 2003 Feb 15. PMID 12600937, Free PMC Article
    2. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    3. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article
    4. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in GPI anchor biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in endoplasmic reticulum-Golgi intermediate compartment membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Metallophosphoesterase 1 homolog
    NP_001251442.2
    • Confirmed by transcript evidence
    NP_001251443.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      10634568..10636028 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001264513.4 → NP_001251442.2  Metallophosphoesterase 1 homolog [Caenorhabditis elegans]

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q95X35
      Conserved Domains (1) summary
      cl13995
      Location:25 → 152
      MPP_superfamily; metallophosphatase superfamily, metallophosphatase domain

    2. NM_001264514.4 → NP_001251443.1  Metallophosphoesterase 1 homolog [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001251443.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      G8JXZ3, Q95X35
      Conserved Domains (1) summary
      cl13995
      Location:51 → 292
      MPP_superfamily; metallophosphatase superfamily, metallophosphatase domain
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q95X35.3

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