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    Y57A10A.29 Succinate dehydrogenase assembly factor 2, mitochondrial [ Caenorhabditis elegans ]

    Gene ID: 174870, updated on 9-Dec-2024

    Summary

    Official Symbol
    Y57A10A.29
    Official Full Name
    Succinate dehydrogenase assembly factor 2, mitochondrial
    Primary source
    WormBase:WBGene00013269
    Locus tag
    CELE_Y57A10A.29
    See related
    AllianceGenome:WB:WBGene00013269
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in mitochondrial electron transport, succinate to ubiquinone; mitochondrial respiratory chain complex II assembly; and tricarboxylic acid cycle. Predicted to be located in mitochondrial matrix. Predicted to be active in mitochondrion. Human ortholog(s) of this gene implicated in paraganglioma. Orthologous to human SDHAF2 (succinate dehydrogenase complex assembly factor 2). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

    See Y57A10A.29 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    2
    Sequence:
    Chromosome: II; NC_003280.10 (12279561..12280595)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene Armadillo repeat-containing protein 4 Neighboring gene Trimeric intracellular cation channel type 1B.2 Neighboring gene Eukaryotic translation initiation factor 4E-5 Neighboring gene RING-type domain-containing protein

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in mitochondrial electron transport, succinate to ubiquinone IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in mitochondrial electron transport, succinate to ubiquinone IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in mitochondrial respiratory chain complex II assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in tricarboxylic acid cycle IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in mitochondrial matrix IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    Succinate dehydrogenase assembly factor 2, mitochondrial
    NP_496607.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      12279561..12280595
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_064206.8NP_496607.1  Succinate dehydrogenase assembly factor 2, mitochondrial [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_496607.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9NA72
      Conserved Domains (1) summary
      pfam03937
      Location:33106
      Sdh5; Flavinator of succinate dehydrogenase