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    ptr-19 SSD domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 191751, updated on 9-Dec-2024

    Summary

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    Official Symbol
    ptr-19
    Official Full Name
    SSD domain-containing protein
    Primary source
    WormBase:WBGene00004233
    Locus tag
    CELE_Y39A1B.2
    See related
    AllianceGenome:WB:WBGene00004233
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Involved in molting cycle. Predicted to be located in membrane. Predicted to be active in cytoplasmic vesicle membrane and plasma membrane. Is expressed in hypodermis; nervous system; and pharynx. Human ortholog(s) of this gene implicated in autistic disorder. Orthologous to human PTCHD1 (patched domain containing 1) and PTCHD4 (patched domain containing 4). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See ptr-19 in Genome Data Viewer
    Location:
    chromosome: III
    Exon count:
    15
    Sequence:
    Chromosome: III; NC_003281.10 (10781853..10791176)

    Chromosome III - NC_003281.10Genomic Context describing neighboring genes Neighboring gene Condensin complex subunit 1 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene C-type LECtin Neighboring gene Major facilitator superfamily (MFS) profile domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003281.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. A C. elegans patched gene, ptc-1, functions in germ-line cytokinesis. Kuwabara PE, et al. Genes Dev, 2000 Aug 1. PMID 10921907, Free PMC Article
    2. The function and expansion of the Patched- and Hedgehog-related homologs in C. elegans. Zugasti O, et al. Genome Res, 2005 Oct. PMID 16204193, Free PMC Article
    3. Meta-Analysis of Caenorhabditis elegans Transcriptomics Implicates Hedgehog-Like Signaling in Host-Microbe Interactions. Zárate-Potes A, et al. Front Microbiol, 2022. PMID 35620104, Free PMC Article
    4. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    5. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in endocytosis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in molting cycle, collagen and cuticulin-based cuticle IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in molting cycle, collagen and cuticulin-based cuticle IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    is_active_in cytoplasmic vesicle membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    SSD domain-containing protein
    NP_001255085.1
    • Confirmed by transcript evidence
    NP_001255086.1
    • Confirmed by transcript evidence
    NP_001255087.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003281.10 Reference assembly

      Range
      10781853..10791176
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001268156.3 → NP_001255085.1  SSD domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001255085.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9XXR9
      Conserved Domains (1) summary
      cl25655
      Location:53 → 858
      Patched; Patched family

    2. NM_001268157.3 → NP_001255086.1  SSD domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001255086.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      D2N110
      Conserved Domains (1) summary
      cl25655
      Location:53 → 680
      Patched; Patched family

    3. NM_001268158.3 → NP_001255087.1  SSD domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_001255087.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      D2N109
      Conserved Domains (1) summary
      cl25655
      Location:53 → 674
      Patched; Patched family
    Nucleotide Protein
    Heading Accession and Version

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