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    abhd-11.2 sn-1-specific diacylglycerol lipase ABHD11 [ Caenorhabditis elegans ]

    Gene ID: 173096, updated on 9-Dec-2024

    Summary

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    Official Symbol
    abhd-11.2
    Official Full Name
    sn-1-specific diacylglycerol lipase ABHD11
    Primary source
    WormBase:WBGene00011029
    Locus tag
    CELE_R05D7.4
    See related
    AllianceGenome:WB:WBGene00011029
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable carboxylic ester hydrolase activity. Predicted to be involved in cellular lipid metabolic process. Predicted to be active in mitochondrion. Orthologous to human ABHD11 (abhydrolase domain containing 11). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See abhd-11.2 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    6
    Sequence:
    Chromosome: I; NC_003279.8 (12181054..12183254, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene SPK domain-containing protein Neighboring gene Transmembrane protein;Transmembrane protein 200C;Uncharacterized protein Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Nematode Specific Peptide family Neighboring gene Uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Defect-buffering cellular plasticity increases robustness of metazoan embryogenesis. Xiao L, et al. Cell Syst, 2022 Aug 17. PMID 35882226
    2. Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules. Cipriani PG, et al. Elife, 2021 Jul 5. PMID 34223818, Free PMC Article
    3. EPIC: software toolkit for elution profile-based inference of protein complexes. Hu LZ, et al. Nat Methods, 2019 Aug. PMID 31308550, Free PMC Article
    4. OrthoList: a compendium of C. elegans genes with human orthologs. Shaye DD, et al. PLoS One, 2011. PMID 21647448, Free PMC Article
    5. OrthoList 2: A New Comparative Genomic Analysis of Human and Caenorhabditis elegans Genes. Kim W, et al. Genetics, 2018 Oct. PMID 30120140, Free PMC Article

    See all (6) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables carboxylic ester hydrolase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in lipid metabolic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in mitochondrion IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    sn-1-specific diacylglycerol lipase ABHD11
    NP_493077.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      12181054..12183254 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_060676.7 → NP_493077.1  sn-1-specific diacylglycerol lipase ABHD11 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_493077.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O45707
      Conserved Domains (1) summary
      PRK10673
      Location:31 → 297
      PRK10673; esterase
    Nucleotide Protein
    Heading Accession and Version

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