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    osr-1 TPR_REGION domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 172161, updated on 9-Dec-2024

    Summary

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    Official Symbol
    osr-1
    Official Full Name
    TPR_REGION domain-containing protein
    Primary source
    WormBase:WBGene00016329
    Locus tag
    CELE_C32E12.3
    See related
    AllianceGenome:WB:WBGene00016329
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Is expressed in hypodermis and intestine. [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See osr-1 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    8
    Sequence:
    Chromosome: I; NC_003279.8 (5200259..5203504, complement)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene FANCM (Fanconi anemia complex component M) homolog Neighboring gene putative 3',5'-cyclic phosphodiesterase pde-5 Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene Transcription factor sem-2 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. p-Coumaric acid improves oxidative and osmosis stress responses in Caenorhabditis elegans. Yue Y, et al. J Sci Food Agric, 2019 Feb. PMID 30047165
    2. Stressed worms: responding to the post-genomics era. Gal TZ, et al. Mol Biochem Parasitol, 2005 Sep. PMID 15955581
    3. Dicarbonyl/L-xylulose reductase (DCXR) producing xylitol regulates egg retention through osmolality control in Caenorhabditis elegans. Kim YN, et al. Anim Cells Syst (Seoul), 2022. PMID 36275448, Free PMC Article
    4. The longevity effect of cranberry extract in Caenorhabditis elegans is modulated by daf-16 and osr-1. Guha S, et al. Age (Dordr), 2013 Oct. PMID 22864793, Free PMC Article
    5. Hormetins, antioxidants and prooxidants: defining quercetin-, caffeic acid- and rosmarinic acid-mediated life extension in C. elegans. Pietsch K, et al. Biogerontology, 2011 Aug. PMID 21503726

    See all (20) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. OSR-1 plays a central role in integrating stress detection and adaptation responses by invoking multiple signaling pathways to promote survival under hyperosmotic environments
      Title: Caenorhabditis elegans OSR-1 regulates behavioral and physiological responses to hyperosmotic environments.
    2. that cranberry supplementation confers increased longevity and stress resistance in C. elegans through pathways modulated by daf-16 and osr-1.
      Title: The longevity effect of cranberry extract in Caenorhabditis elegans is modulated by daf-16 and osr-1.
    Submit: New GeneRIF Correction

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    General protein information

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    Preferred Names
    TPR_REGION domain-containing protein
    NP_491545.2
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      5200259..5203504 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_059144.7 → NP_491545.2  TPR_REGION domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_491545.2

      Status: REVIEWED

      UniProtKB/TrEMBL
      G5EEJ4
    Nucleotide Protein
    Heading Accession and Version

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