rpl-3 Large ribosomal subunit protein uL3 [Caenorhabditis elegans] - Gene

Summary

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Official Symbol: rpl-3
Official Full Name: Large ribosomal subunit protein uL3
Primary source: WormBase:WBGene00004414
Locus tag: CELE_F13B10.2
See related: AllianceGenome:WB:WBGene00004414
Gene type: protein coding
RefSeq status: REVIEWED
Organism: Caenorhabditis elegans (strain: Bristol N2)
Lineage: Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
Summary: Predicted to enable RNA binding activity. Predicted to be a structural constituent of ribosome. Predicted to be involved in translation. Predicted to be located in cytoplasm and ribosome. Predicted to be part of cytosolic large ribosomal subunit. Human ortholog(s) of this gene implicated in dilated cardiomyopathy 2D. Orthologous to several human genes including RPL3 (ribosomal protein L3). [provided by Alliance of Genome Resources, Dec 2024]
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Genomic context

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See rpl-3 in Genome Data Viewer

Location:: chromosome: III

Exon count:: 4

Sequence:: Chromosome: III; NC_003281.10 (3867854..3869587)

Chromosome III - NC_003281.10 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:: NC_003281.10

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Pathways from PubChem

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Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

F13B10.2 (e-PCR)
- UniSTS:306019

Homology

Orthologs from OrthoDB

Gene Ontology Provided by WormBase

Function	Evidence Code	Pubs
enables RNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables structural constituent of ribosome	IBA Inferred from Biological aspect of Ancestor more info
enables structural constituent of ribosome	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
involved_in translation	IBA Inferred from Biological aspect of Ancestor more info
involved_in translation	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
part_of cytosolic large ribosomal subunit	IBA Inferred from Biological aspect of Ancestor more info
part_of ribonucleoprotein complex	IEA Inferred from Electronic Annotation more info
located_in ribosome	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: Large ribosomal subunit protein uL3

NP_001021254.1

Confirmed by transcript evidence

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

NC_003281.10 Reference assembly

Range

3867854..3869587

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

NM_001026083.7 → NP_001021254.1 Large ribosomal subunit protein uL3 [Caenorhabditis elegans]

See identical proteins and their annotated locations for NP_001021254.1

Status: REVIEWED

UniProtKB/Swiss-Prot

P50880

UniProtKB/TrEMBL

G5ECE5

Conserved Domains (2) summary

PTZ00103
Location:1 → 397

PTZ00103; 60S ribosomal protein L3; Provisional

cl00324
Location:3 → 372

RplC; Ribosomal protein L3 [Translation, ribosomal structure and biogenesis]