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    rps-6 Small ribosomal subunit protein eS6 [ Caenorhabditis elegans ]

    Gene ID: 173260, updated on 9-Dec-2024

    Summary

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    Official Symbol
    rps-6
    Official Full Name
    Small ribosomal subunit protein eS6
    Primary source
    WormBase:WBGene00004475
    Locus tag
    CELE_Y71A12B.1
    See related
    AllianceGenome:WB:WBGene00004475
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be a structural constituent of ribosome. Involved in determination of adult lifespan. Predicted to be located in cytoplasm; nucleolus; and ribosome. Predicted to be part of small-subunit processome. Orthologous to human RPS6 (ribosomal protein S6). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See rps-6 in Genome Data Viewer
    Location:
    chromosome: I
    Exon count:
    3
    Sequence:
    Chromosome: I; NC_003279.8 (13952161..13953203)

    Chromosome I - NC_003279.8Genomic Context describing neighboring genes Neighboring gene Ubiquitin carboxyl-terminal hydrolase Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene PB1 domain-containing protein Neighboring gene ncRNA Neighboring gene pseudo

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003279.8

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Folate receptor overexpression induces toxicity in a diet-dependent manner in C. elegans. Shrestha B, et al. Sci Rep, 2024 Jan 11. PMID 38212621, Free PMC Article
    2. Increased sensitivity and accuracy of a single-stranded DNA splint-mediated ligation assay (sPAT) reveals poly(A) tail length dynamics of developmentally regulated mRNAs. Minasaki R, et al. RNA Biol, 2014. PMID 24526206, Free PMC Article
    3. The Caenorhabditis elegans gene mfap-1 encodes a nuclear protein that affects alternative splicing. Ma L, et al. PLoS Genet, 2012. PMID 22829783, Free PMC Article
    4. Large-scale analysis of gene function in Caenorhabditis elegans by high-throughput RNAi. Maeda I, et al. Curr Biol, 2001 Feb 6. PMID 11231151
    5. Mass spectrometry-based shotgun proteomic analysis of C. elegans protein complexes. Fonslow BR, et al. WormBook, 2014 Jun 24. PMID 24967700, Free PMC Article

    See all (28) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables structural constituent of ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in determination of adult lifespan IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in ribosomal small subunit biogenesis ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    involved_in translation IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    part_of small-subunit processome ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  

    General protein information

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    Preferred Names
    Small ribosomal subunit protein eS6
    NP_493435.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003279.8 Reference assembly

      Range
      13952161..13953203
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_061034.9 → NP_493435.1  Small ribosomal subunit protein eS6 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_493435.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q9NEN6
      Conserved Domains (1) summary
      cl00931
      Location:1 → 219
      Ribosomal_S6e; Ribosomal protein S6e
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9NEN6.1

    Gene LinkOut

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