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    pes-9 Peptidase M20 dimerization domain-containing protein [ Caenorhabditis elegans ]

    Gene ID: 179963, updated on 9-Dec-2024

    Summary

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    Official Symbol
    pes-9
    Official Full Name
    Peptidase M20 dimerization domain-containing protein
    Primary source
    WormBase:WBGene00003982
    Locus tag
    CELE_R11H6.1
    See related
    AllianceGenome:WB:WBGene00003982
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable peptidase activity. Predicted to be involved in proteolysis. Is expressed in hypodermis and intestine. Orthologous to human CNDP2 (carnosine dipeptidase 2). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See pes-9 in Genome Data Viewer
    Location:
    chromosome: V
    Exon count:
    3
    Sequence:
    Chromosome: V; NC_003283.11 (14595314..14597034, complement)

    Chromosome V - NC_003283.11Genomic Context describing neighboring genes Neighboring gene Serine/threonine specific protein phosphatases domain-containing protein Neighboring gene pseudo Neighboring gene Serine incorporator Neighboring gene ncRNA Neighboring gene GLOBIN domain-containing protein;Globin family profile domain-containing protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003283.11

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Molecular markers of differentiation in Caenorhabditis elegans obtained by promoter trapping. Young JM, et al. Dev Dyn, 1993 Feb. PMID 8364222
    2. A glutathione peroxidase, intracellular peptidases and the TOR complexes regulate peptide transporter PEPT-1 in C. elegans. Benner J, et al. PLoS One, 2011. PMID 21980510, Free PMC Article
    3. Target-selected gene inactivation in Caenorhabditis elegans by using a frozen transposon insertion mutant bank. Zwaal RR, et al. Proc Natl Acad Sci U S A, 1993 Aug 15. PMID 8395047, Free PMC Article
    4. SUMO peptidase ULP-4 regulates mitochondrial UPR-mediated innate immunity and lifespan extension. Gao K, et al. Elife, 2019 Jan 15. PMID 30642431, Free PMC Article
    5. Depletion of endogenously biotinylated carboxylases enhances the sensitivity of TurboID-mediated proximity labeling in Caenorhabditis elegans. Artan M, et al. J Biol Chem, 2022 Sep. PMID 35933017, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables metallodipeptidase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables peptidase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in proteolysis IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    Peptidase M20 dimerization domain-containing protein
    NP_506610.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003283.11 Reference assembly

      Range
      14595314..14597034 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_074209.9 → NP_506610.1  Peptidase M20 dimerization domain-containing protein [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_506610.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      O18000
      Conserved Domains (1) summary
      cd05676
      Location:8 → 473
      M20_dipept_like_CNDP; M20 cytosolic nonspecific dipeptidases including anserinase and serum carnosinase
    Nucleotide Protein
    Heading Accession and Version

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