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    M110.7 Putative patatin-like phospholipase domain-containing protein M110.7 [ Caenorhabditis elegans ]

    Gene ID: 187474, updated on 9-Dec-2024

    Summary

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    Official Symbol
    M110.7
    Official Full Name
    Putative patatin-like phospholipase domain-containing protein M110.7
    Primary source
    WormBase:WBGene00010915
    Locus tag
    CELE_M110.7
    See related
    AllianceGenome:WB:WBGene00010915
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to enable lysophospholipase activity. Predicted to be involved in lipid catabolic process. Predicted to be located in membrane. Predicted to be active in endoplasmic reticulum. Human ortholog(s) of this gene implicated in Boucher-Neuhauser syndrome; Laurence-Moon syndrome; Oliver-McFarlane syndrome; and hereditary spastic paraplegia 39. Orthologous to human PNPLA6 (patatin like phospholipase domain containing 6) and PNPLA7 (patatin like phospholipase domain containing 7). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See M110.7 in Genome Data Viewer
    Location:
    chromosome: II
    Exon count:
    20
    Sequence:
    Chromosome: II; NC_003280.10 (8232789..8237252)

    Chromosome II - NC_003280.10Genomic Context describing neighboring genes Neighboring gene MIF4G domain-containing protein Neighboring gene PID domain-containing protein Neighboring gene DUF148 domain-containing protein Neighboring gene ncRNA Neighboring gene Neuropeptide-Like Protein Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003280.10

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Function Evidence Code Pubs
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables lysophospholipase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables lysophospholipase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in lipid catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in lipid metabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    is_active_in endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    Putative patatin-like phospholipase domain-containing protein M110.7
    NP_495734.3
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003280.10 Reference assembly

      Range
      8232789..8237252
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_063333.4 → NP_495734.3  Putative patatin-like phospholipase domain-containing protein M110.7 [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_495734.3

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q20023, Q21534
      Conserved Domains (4) summary
      COG0664
      Location:423 → 543
      Crp; cAMP-binding domain of CRP or a regulatory subunit of cAMP-dependent protein kinases [Signal transduction mechanisms]
      COG1752
      Location:756 → 1046
      RssA; Predicted acylesterase/phospholipase RssA, containd patatin domain [General function prediction only]
      cd00038
      Location:444 → 538
      CAP_ED; effector domain of the CAP family of transcription factors; members include CAP (or cAMP receptor protein (CRP)), which binds cAMP, FNR (fumarate and nitrate reduction), which uses an iron-sulfur cluster to sense oxygen) and CooA, a heme containing CO ...
      cl11396
      Location:752 → 1040
      Patatin_and_cPLA2; Patatins and Phospholipases
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q21534.3

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