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    T03G6.3 glycerophosphocholine cholinephosphodiesterase [ Caenorhabditis elegans ]

    Gene ID: 180561, updated on 9-Dec-2024

    Summary

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    Official Symbol
    T03G6.3
    Official Full Name
    glycerophosphocholine cholinephosphodiesterase
    Primary source
    WormBase:WBGene00020195
    Locus tag
    CELE_T03G6.3
    See related
    AllianceGenome:WB:WBGene00020195
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Caenorhabditis elegans (strain: Bristol N2)
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida; Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis
    Summary
    Predicted to be involved in lipid catabolic process. Located in I band and striated muscle dense body. Is expressed in body wall musculature and vulval muscle. Orthologous to human ENPP6 (ectonucleotide pyrophosphatase/phosphodiesterase 6). [provided by Alliance of Genome Resources, Dec 2024]
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    Genomic context

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    See T03G6.3 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    10
    Sequence:
    Chromosome: X; NC_003284.9 (2610826..2615726, complement)

    Chromosome X - NC_003284.9Genomic Context describing neighboring genes Neighboring gene Uncharacterized protein Neighboring gene Nuclear hormone receptor family member nhr-40 Neighboring gene YitH/HolE acetyltransferase (GNAT) domain-containing protein Neighboring gene tRNA-Gly Neighboring gene ncRNA Neighboring gene ncRNA Neighboring gene BAI1-associated protein 3 Neighboring gene ncRNA

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003284.9

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Determination of the mobility of novel and established Caenorhabditis elegans sarcomeric proteins in vivo. Ghosh SR, et al. Eur J Cell Biol, 2010 Jun. PMID 20226563
    2. Determining the sub-cellular localization of proteins within Caenorhabditis elegans body wall muscle. Meissner B, et al. PLoS One, 2011. PMID 21611156, Free PMC Article
    3. Genome sequence of the nematode C. elegans: a platform for investigating biology. C. elegans Sequencing Consortium. Science, 1998 Dec 11. PMID 9851916

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Three genes, T03G6.3, C46G7.2 and K04A8.6, coding for novel protein components of the Caenorhabditis elegans sarcomere, were studied
      Title: Determination of the mobility of novel and established Caenorhabditis elegans sarcomeric proteins in vivo.
    Submit: New GeneRIF Correction

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by WormBase

    Process Evidence Code Pubs
    involved_in lipid catabolic process IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in I band IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in sarcoplasmic reticulum HDA PubMed 
    located_in striated muscle dense body IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    glycerophosphocholine cholinephosphodiesterase
    NP_508470.1
    • Confirmed by transcript evidence

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003284.9 Reference assembly

      Range
      2610826..2615726 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_076069.8 → NP_508470.1  glycerophosphocholine cholinephosphodiesterase [Caenorhabditis elegans]

      See identical proteins and their annotated locations for NP_508470.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q22129
      Conserved Domains (2) summary
      pfam01663
      Location:24 → 366
      Phosphodiest; Type I phosphodiesterase / nucleotide pyrophosphatase
      cd16018
      Location:22 → 413
      Enpp; Ectonucleotide pyrophosphatase/phosphodiesterase, also called autotaxin
    Nucleotide Protein
    Heading Accession and Version

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