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    Ppfia2 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2 [ Mus musculus (house mouse) ]

    Gene ID: 327814, updated on 9-Dec-2024

    Summary

    Official Symbol
    Ppfia2provided by MGI
    Official Full Name
    protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 2provided by MGI
    Primary source
    MGI:MGI:2443834
    See related
    Ensembl:ENSMUSG00000053825 AllianceGenome:MGI:2443834
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    mKIAA4112; 5330438O12; B230207K17Rik; E130120L08Rik
    Summary
    Predicted to be a structural constituent of presynapse. Predicted to be involved in several processes, including dense core granule cytoskeletal transport; regulation of dendritic spine morphogenesis; and regulation of synaptic vesicle exocytosis. Is active in glutamatergic synapse and presynaptic cytosol. Is expressed in several structures, including adrenal gland; brain; pancreas; retina layer; and testis. Orthologous to human PPFIA2 (PTPRF interacting protein alpha 2). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in frontal lobe adult (RPKM 9.9), CNS E18 (RPKM 9.1) and 5 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Ppfia2 in Genome Data Viewer
    Location:
    10 D1; 10 55.39 cM
    Exon count:
    36
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (106305129..106769329)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (106469500..106933468)

    Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_27768 Neighboring gene heterogeneous nuclear ribonucleoprotein A1 pseudogene Neighboring gene STARR-seq mESC enhancer starr_27770 Neighboring gene STARR-seq mESC enhancer starr_27771 Neighboring gene STARR-seq mESC enhancer starr_27772 Neighboring gene STARR-seq mESC enhancer starr_27773 Neighboring gene ribosomal protein S15A, pseudogene 1 Neighboring gene STARR-seq mESC enhancer starr_27774 Neighboring gene STARR-seq mESC enhancer starr_27775 Neighboring gene STARR-seq mESC enhancer starr_27776 Neighboring gene STARR-seq mESC enhancer starr_27778 Neighboring gene RIKEN cDNA 4930532I03 gene Neighboring gene olfactory receptor family 8 subfamily O member 1, pseudogene 1 Neighboring gene STARR-seq mESC enhancer starr_27779 Neighboring gene nucleolin pseudogene Neighboring gene STARR-seq mESC enhancer starr_27780 Neighboring gene sulfotransferase family, cytosolic, 1C, member 2 pseudogene Neighboring gene acyl-CoA synthetase short-chain family member 3 Neighboring gene predicted gene, 18040

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 
    • Targeted (3)  1 citation

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • KIAA4112

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein-containing complex binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables structural constituent of presynapse ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in dense core granule cytoskeletal transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in dense core granule cytoskeletal transport ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in regulation of dendritic spine development ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of dendritic spine development ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in regulation of dendritic spine morphogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of dendritic spine morphogenesis ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in regulation of synaptic vesicle exocytosis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in synapse organization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in axon IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cell surface IEA
    Inferred from Electronic Annotation
    more info
     
    located_in dendritic spine ISO
    Inferred from Sequence Orthology
    more info
     
    located_in dendritic spine ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    is_active_in glutamatergic synapse IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in glutamatergic synapse ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in postsynaptic specialization ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in presynaptic active zone IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in presynaptic cytosol IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in presynaptic membrane ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in synapse IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in synapse IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in synaptic vesicle ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    liprin-alpha-2
    Names
    PTPRF interacting protein alpha 2
    protein tyrosine phosphatase receptor type f polypeptide-interacting protein alpha-2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001205341.1NP_001192270.1  liprin-alpha-2 isoform 1

      See identical proteins and their annotated locations for NP_001192270.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      AC140785, CD802610, EU568870
      Consensus CDS
      CCDS56746.1
      UniProtKB/Swiss-Prot
      Q6P1D2, Q8BN73, Q8BSS9
      UniProtKB/TrEMBL
      B8QI34
      Related
      ENSMUSP00000151545.2, ENSMUST00000217854.2
      Conserved Domains (6) summary
      cd09562
      Location:895965
      SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
      cd09565
      Location:10191084
      SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
      cd09568
      Location:11041175
      SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
      smart00454
      Location:895961
      SAM; Sterile alpha motif
      pfam09728
      Location:265533
      Taxilin; Myosin-like coiled-coil protein
      cl02488
      Location:362536
      SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    2. NM_001359672.1NP_001346601.1  liprin-alpha-2 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC135115, AC140785, AK043021, BC065133, CD802610
      UniProtKB/Swiss-Prot
      Q6P1D2, Q8BN73, Q8BSS9
      Conserved Domains (4) summary
      cd09562
      Location:898968
      SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
      cd09565
      Location:10221087
      SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
      cd09568
      Location:11071178
      SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
      cl25732
      Location:201540
      SMC_N; RecF/RecN/SMC N terminal domain
    3. NM_001359673.1NP_001346602.1  liprin-alpha-2 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AC140785, CD802610, EU568870
      UniProtKB/Swiss-Prot
      Q6P1D2, Q8BN73, Q8BSS9
      Conserved Domains (4) summary
      cd09562
      Location:895965
      SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
      cd09565
      Location:10131078
      SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
      cd09568
      Location:10981169
      SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
      cl25732
      Location:201533
      SMC_N; RecF/RecN/SMC N terminal domain
    4. NM_001359674.1NP_001346603.1  liprin-alpha-2 isoform 5

      Status: VALIDATED

      Source sequence(s)
      AC140785, AK043021, BC065133, CD802610
      UniProtKB/Swiss-Prot
      Q6P1D2, Q8BN73, Q8BSS9
      Conserved Domains (4) summary
      cd09562
      Location:894964
      SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
      cd09565
      Location:10181083
      SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
      cd09568
      Location:11031174
      SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
      cl25732
      Location:201533
      SMC_N; RecF/RecN/SMC N terminal domain
    5. NM_001359675.1NP_001346604.1  liprin-alpha-2 isoform 6

      Status: VALIDATED

      Source sequence(s)
      AC140785, AK043021, BC065133, CD802610, EU568870
      UniProtKB/Swiss-Prot
      Q6P1D2, Q8BN73, Q8BSS9
      Conserved Domains (4) summary
      cd09562
      Location:895965
      SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
      cd09565
      Location:10131078
      SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
      cd09568
      Location:10981169
      SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
      cl25732
      Location:201533
      SMC_N; RecF/RecN/SMC N terminal domain
    6. NM_001359676.1NP_001346605.1  liprin-alpha-2 isoform 7

      Status: VALIDATED

      Source sequence(s)
      AC140785, AK043021, BC065133, CD802610
      UniProtKB/Swiss-Prot
      Q6P1D2, Q8BN73, Q8BSS9
      Conserved Domains (4) summary
      cd09562
      Location:894964
      SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
      cd09565
      Location:10121077
      SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
      cd09568
      Location:10971168
      SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
      cl25732
      Location:201533
      SMC_N; RecF/RecN/SMC N terminal domain
    7. NM_001359677.1NP_001346606.1  liprin-alpha-2 isoform 8

      Status: VALIDATED

      Source sequence(s)
      AC123814, AC135115, AW046469, BY235970, CD802610, EU568870
      UniProtKB/Swiss-Prot
      Q6P1D2, Q8BN73, Q8BSS9
      Conserved Domains (4) summary
      cd09562
      Location:828898
      SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
      cd09565
      Location:9521017
      SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
      cd09568
      Location:10371108
      SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
      COG1196
      Location:127466
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    8. NM_001359678.1NP_001346607.1  liprin-alpha-2 isoform 9

      Status: VALIDATED

      Source sequence(s)
      AC123814, AC135115, AW046469, BY235970, CD802610, EU568870
      UniProtKB/Swiss-Prot
      Q6P1D2, Q8BN73, Q8BSS9
      Conserved Domains (4) summary
      cd09562
      Location:827897
      SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
      cd09565
      Location:9511016
      SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
      cd09568
      Location:10361107
      SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
      cl25732
      Location:127466
      SMC_N; RecF/RecN/SMC N terminal domain
    9. NM_001359679.1NP_001346608.1  liprin-alpha-2 isoform 10

      Status: VALIDATED

      Source sequence(s)
      AC123814, AC135115, AW046469, BY235970, CD802610, EU568870
      UniProtKB/Swiss-Prot
      Q6P1D2, Q8BN73, Q8BSS9
      Conserved Domains (4) summary
      cd09562
      Location:825895
      SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
      cd09565
      Location:9491014
      SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
      cd09568
      Location:10341105
      SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
      cl25732
      Location:127466
      SMC_N; RecF/RecN/SMC N terminal domain
    10. NM_001359680.1NP_001346609.1  liprin-alpha-2 isoform 11

      Status: VALIDATED

      Source sequence(s)
      AC123814, AC135115, AW046469, BY235970, CD802610, EU568870
      UniProtKB/Swiss-Prot
      Q6P1D2, Q8BN73, Q8BSS9
      Conserved Domains (4) summary
      cd09562
      Location:824894
      SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
      cd09565
      Location:9481013
      SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
      cd09568
      Location:10331104
      SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
      COG1196
      Location:127459
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    11. NM_001359681.1NP_001346610.1  liprin-alpha-2 isoform 12

      Status: VALIDATED

      Source sequence(s)
      AC123814, AC135115, AW046469, BY235970, CD802610, EU568870
      UniProtKB/Swiss-Prot
      Q6P1D2, Q8BN73, Q8BSS9
      Conserved Domains (4) summary
      cd09562
      Location:823893
      SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
      cd09565
      Location:9471012
      SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
      cd09568
      Location:10321103
      SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
      cl25732
      Location:127459
      SMC_N; RecF/RecN/SMC N terminal domain
    12. NM_001359682.1NP_001346611.1  liprin-alpha-2 isoform 13

      Status: VALIDATED

      Source sequence(s)
      AC123814, AC135115, AW046469, BY235970, CD802610, EU568870
      UniProtKB/Swiss-Prot
      Q6P1D2, Q8BN73, Q8BSS9
      Conserved Domains (4) summary
      cd09562
      Location:828898
      SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
      cd09565
      Location:9461011
      SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
      cd09568
      Location:10311102
      SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
      COG1196
      Location:127466
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    13. NM_001359683.1NP_001346612.1  liprin-alpha-2 isoform 14

      Status: VALIDATED

      Source sequence(s)
      AC123814, AW046469, BY235970, CD802610, EU568870
      UniProtKB/Swiss-Prot
      Q6P1D2, Q8BN73, Q8BSS9
      Conserved Domains (4) summary
      cd09562
      Location:821891
      SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
      cd09565
      Location:9451010
      SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
      cd09568
      Location:10301101
      SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
      cl25732
      Location:127459
      SMC_N; RecF/RecN/SMC N terminal domain
    14. NM_001359684.1NP_001346613.1  liprin-alpha-2 isoform 15

      Status: VALIDATED

      Source sequence(s)
      AC123814, AW046469, BY235970, CD802610, EU568870
      UniProtKB/Swiss-Prot
      Q6P1D2, Q8BN73, Q8BSS9
      Conserved Domains (4) summary
      cd09562
      Location:820890
      SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
      cd09565
      Location:9441009
      SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
      cd09568
      Location:10291100
      SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
      cl25732
      Location:127459
      SMC_N; RecF/RecN/SMC N terminal domain
    15. NM_001359685.1NP_001346614.1  liprin-alpha-2 isoform 16

      Status: VALIDATED

      Source sequence(s)
      AC123814, AC135115, AW046469, BY235970, CD802610, EU568870
      UniProtKB/Swiss-Prot
      Q6P1D2, Q8BN73, Q8BSS9
      Conserved Domains (4) summary
      cd09562
      Location:825895
      SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
      cd09565
      Location:9431008
      SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
      cd09568
      Location:10281099
      SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
      cl25732
      Location:127466
      SMC_N; RecF/RecN/SMC N terminal domain
    16. NM_001359686.1NP_001346615.1  liprin-alpha-2 isoform 17

      Status: VALIDATED

      Source sequence(s)
      AC123814, AC135115, AW046469, BY235970, CD802610, EU568870
      UniProtKB/Swiss-Prot
      Q6P1D2, Q8BN73, Q8BSS9
      Conserved Domains (4) summary
      cd09562
      Location:824894
      SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
      cd09565
      Location:9421007
      SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
      cd09568
      Location:10271098
      SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
      COG1196
      Location:127459
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    17. NM_001359687.1NP_001346616.1  liprin-alpha-2 isoform 18

      Status: VALIDATED

      Source sequence(s)
      AC123814, AC135115, AW046469, BY235970, CD802610, EU568870
      UniProtKB/Swiss-Prot
      Q6P1D2, Q8BN73, Q8BSS9
      Conserved Domains (4) summary
      cd09562
      Location:828898
      SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
      cd09565
      Location:9521017
      SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
      cd09568
      Location:10371108
      SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
      cl25732
      Location:127466
      SMC_N; RecF/RecN/SMC N terminal domain
    18. NM_001359688.1NP_001346617.1  liprin-alpha-2 isoform 19

      Status: VALIDATED

      Source sequence(s)
      AC123814, AC135115, AW046469, BY235970, CD802610, EU568870
      UniProtKB/Swiss-Prot
      Q6P1D2, Q8BN73, Q8BSS9
      Conserved Domains (4) summary
      cd09562
      Location:823893
      SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
      cd09565
      Location:9411006
      SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
      cd09568
      Location:10261097
      SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
      COG1196
      Location:127459
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    19. NM_001359689.1NP_001346618.1  liprin-alpha-2 isoform 20

      Status: VALIDATED

      Source sequence(s)
      AC123814, AC135115, AW046469, BY235970, CD802610, EU568870
      UniProtKB/Swiss-Prot
      Q6P1D2, Q8BN73, Q8BSS9
      Conserved Domains (4) summary
      cd09562
      Location:824894
      SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
      cd09565
      Location:9481013
      SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
      cd09568
      Location:10331104
      SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
      cl25732
      Location:127459
      SMC_N; RecF/RecN/SMC N terminal domain
    20. NM_001359690.1NP_001346619.1  liprin-alpha-2 isoform 21

      Status: VALIDATED

      Source sequence(s)
      AC123814, AW046469, BY235970, CD802610, EU568870
      UniProtKB/Swiss-Prot
      Q6P1D2, Q8BN73, Q8BSS9
      Conserved Domains (4) summary
      cd09562
      Location:820890
      SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
      cd09565
      Location:9381003
      SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
      cd09568
      Location:10231094
      SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
      cl25732
      Location:127459
      SMC_N; RecF/RecN/SMC N terminal domain
    21. NM_001359691.1NP_001346620.1  liprin-alpha-2 isoform 22

      Status: VALIDATED

      Source sequence(s)
      AC123814, AW046469, BY235970, CD802610, EU568870
      UniProtKB/Swiss-Prot
      Q6P1D2, Q8BN73, Q8BSS9
      Conserved Domains (4) summary
      cd09562
      Location:821891
      SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
      cd09565
      Location:9391004
      SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
      cd09568
      Location:10241095
      SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
      cl25732
      Location:127459
      SMC_N; RecF/RecN/SMC N terminal domain
    22. NM_001359692.1NP_001346621.1  liprin-alpha-2 isoform 23

      Status: VALIDATED

      Source sequence(s)
      AC123814, AC135115, AW046469, BY235970, CD802610, EU568870
      UniProtKB/Swiss-Prot
      Q6P1D2, Q8BN73, Q8BSS9
      Conserved Domains (4) summary
      cd09562
      Location:825895
      SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
      cd09565
      Location:9491014
      SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
      cd09568
      Location:10341105
      SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
      cl25732
      Location:127466
      SMC_N; RecF/RecN/SMC N terminal domain
    23. NM_001359693.1NP_001346622.1  liprin-alpha-2 isoform 24

      Status: VALIDATED

      Source sequence(s)
      AC123814, AC135115, AW046469, BY235970, CD802610, EU568870
      UniProtKB/Swiss-Prot
      Q6P1D2, Q8BN73, Q8BSS9
      Conserved Domains (4) summary
      cd09562
      Location:823893
      SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
      cd09565
      Location:9471012
      SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
      cd09568
      Location:10321103
      SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
      cl25732
      Location:127459
      SMC_N; RecF/RecN/SMC N terminal domain
    24. NM_001359694.1NP_001346623.1  liprin-alpha-2 isoform 25

      Status: VALIDATED

      Source sequence(s)
      AC123814, AW046469, BY235970, CD802610, EU568870
      UniProtKB/Swiss-Prot
      Q6P1D2, Q8BN73, Q8BSS9
      Conserved Domains (4) summary
      cd09562
      Location:821891
      SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
      cd09565
      Location:9451010
      SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
      cd09568
      Location:10301101
      SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
      cl25732
      Location:127459
      SMC_N; RecF/RecN/SMC N terminal domain
    25. NM_001359695.1NP_001346624.1  liprin-alpha-2 isoform 26

      Status: VALIDATED

      Source sequence(s)
      AC123814, AW046469, BY235970, CD802610, EU568870
      UniProtKB/Swiss-Prot
      Q6P1D2, Q8BN73, Q8BSS9
      Conserved Domains (4) summary
      cd09562
      Location:820890
      SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
      cd09565
      Location:9441009
      SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
      cd09568
      Location:10291100
      SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
      cl25732
      Location:127459
      SMC_N; RecF/RecN/SMC N terminal domain
    26. NM_001359696.1NP_001346625.1  liprin-alpha-2 isoform 27

      Status: VALIDATED

      Source sequence(s)
      AC123814, AC135115, AW046469, BY235970, CD802610, EU568870
      UniProtKB/Swiss-Prot
      Q6P1D2, Q8BN73, Q8BSS9
      Conserved Domains (4) summary
      cd09562
      Location:823893
      SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
      cd09565
      Location:9411006
      SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
      cd09568
      Location:10261097
      SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
      cl25732
      Location:127459
      SMC_N; RecF/RecN/SMC N terminal domain
    27. NM_001359697.1NP_001346626.1  liprin-alpha-2 isoform 28

      Status: VALIDATED

      Source sequence(s)
      AC123814, AW046469, BY235970, CD802610, EU568870
      UniProtKB/Swiss-Prot
      Q6P1D2, Q8BN73, Q8BSS9
      Conserved Domains (4) summary
      cd09562
      Location:821891
      SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
      cd09565
      Location:9391004
      SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
      cd09568
      Location:10241095
      SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
      cl25732
      Location:127459
      SMC_N; RecF/RecN/SMC N terminal domain
    28. NM_001359698.1NP_001346627.1  liprin-alpha-2 isoform 29

      Status: VALIDATED

      Source sequence(s)
      AC123814, AW046469, BY235970, CD802610, EU568870
      UniProtKB/Swiss-Prot
      Q6P1D2, Q8BN73, Q8BSS9
      Conserved Domains (4) summary
      cd09562
      Location:820890
      SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
      cd09565
      Location:9381003
      SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
      cd09568
      Location:10231094
      SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
      cl25732
      Location:127459
      SMC_N; RecF/RecN/SMC N terminal domain
    29. NM_177373.4NP_796347.2  liprin-alpha-2 isoform 2

      See identical proteins and their annotated locations for NP_796347.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate in-frame splice site in the central coding region, compared to variant 1. This results in a shorter protein (isoform 2), compared to isoform 1.
      Source sequence(s)
      AC140785, AK043021, BC065133, CD802610
      Consensus CDS
      CCDS88082.1
      UniProtKB/Swiss-Prot
      Q6P1D2, Q8BN73, Q8BSS9
      UniProtKB/TrEMBL
      F7CYX4
      Related
      ENSMUSP00000029404.11, ENSMUST00000029404.17
      Conserved Domains (6) summary
      cd09562
      Location:894964
      SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
      cd09565
      Location:10181083
      SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
      cd09568
      Location:11031174
      SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
      smart00454
      Location:894960
      SAM; Sterile alpha motif
      pfam09728
      Location:265533
      Taxilin; Myosin-like coiled-coil protein
      cl02488
      Location:362536
      SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000076.7 Reference GRCm39 C57BL/6J

      Range
      106305129..106769329
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036155828.1XP_036011721.1  liprin-alpha-2 isoform X1

      UniProtKB/Swiss-Prot
      Q6P1D2, Q8BN73, Q8BSS9
      Conserved Domains (4) summary
      cd09562
      Location:902972
      SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
      cd09565
      Location:10261091
      SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
      cd09568
      Location:11111182
      SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
      COG1196
      Location:201540
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    2. XM_036155827.1XP_036011720.1  liprin-alpha-2 isoform X1

      UniProtKB/Swiss-Prot
      Q6P1D2, Q8BN73, Q8BSS9
      Conserved Domains (4) summary
      cd09562
      Location:902972
      SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
      cd09565
      Location:10261091
      SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
      cd09568
      Location:11111182
      SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
      COG1196
      Location:201540
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    3. XM_030245137.2XP_030100997.1  liprin-alpha-2 isoform X1

      UniProtKB/Swiss-Prot
      Q6P1D2, Q8BN73, Q8BSS9
      Conserved Domains (4) summary
      cd09562
      Location:902972
      SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
      cd09565
      Location:10261091
      SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
      cd09568
      Location:11111182
      SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
      COG1196
      Location:201540
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    4. XM_036155835.1XP_036011728.1  liprin-alpha-2 isoform X19

      UniProtKB/Swiss-Prot
      Q6P1D2, Q8BN73, Q8BSS9
      Conserved Domains (4) summary
      cd09562
      Location:877947
      SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
      cd09565
      Location:10011066
      SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
      cd09568
      Location:10861157
      SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
      COG1196
      Location:168515
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    5. XM_036155826.1XP_036011719.1  liprin-alpha-2 isoform X1

      UniProtKB/Swiss-Prot
      Q6P1D2, Q8BN73, Q8BSS9
      Conserved Domains (4) summary
      cd09562
      Location:902972
      SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
      cd09565
      Location:10261091
      SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
      cd09568
      Location:11111182
      SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
      COG1196
      Location:201540
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    6. XM_006513776.5XP_006513839.1  liprin-alpha-2 isoform X4

      UniProtKB/Swiss-Prot
      Q6P1D2, Q8BN73, Q8BSS9
      Conserved Domains (4) summary
      cd09562
      Location:898968
      SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
      cd09565
      Location:10221087
      SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
      cd09568
      Location:11071178
      SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
      COG1196
      Location:201533
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    7. XM_036155830.1XP_036011723.1  liprin-alpha-2 isoform X4

      UniProtKB/Swiss-Prot
      Q6P1D2, Q8BN73, Q8BSS9
      Conserved Domains (4) summary
      cd09562
      Location:898968
      SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
      cd09565
      Location:10221087
      SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
      cd09568
      Location:11071178
      SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
      COG1196
      Location:201533
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    8. XM_036155836.1XP_036011729.1  liprin-alpha-2 isoform X23

      UniProtKB/Swiss-Prot
      Q6P1D2, Q8BN73, Q8BSS9
      Conserved Domains (4) summary
      cd09562
      Location:828898
      SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
      cd09565
      Location:9521017
      SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
      cd09568
      Location:10371108
      SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
      COG1196
      Location:127466
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    9. XM_036155838.1XP_036011731.1  liprin-alpha-2 isoform X25

      UniProtKB/Swiss-Prot
      Q6P1D2, Q8BN73, Q8BSS9
      Conserved Domains (4) summary
      cd09562
      Location:828898
      SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
      cd09565
      Location:9461011
      SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
      cd09568
      Location:10311102
      SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
      COG1196
      Location:127466
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    10. XM_036155837.1XP_036011730.1  liprin-alpha-2 isoform X24

      UniProtKB/Swiss-Prot
      Q6P1D2, Q8BN73, Q8BSS9
      Conserved Domains (4) summary
      cd09562
      Location:824894
      SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
      cd09565
      Location:9481013
      SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
      cd09568
      Location:10331104
      SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
      COG1196
      Location:127459
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    11. XM_036155839.1XP_036011732.1  liprin-alpha-2 isoform X26

      UniProtKB/Swiss-Prot
      Q6P1D2, Q8BN73, Q8BSS9
      Conserved Domains (4) summary
      cd09562
      Location:824894
      SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
      cd09565
      Location:9421007
      SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
      cd09568
      Location:10271098
      SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
      COG1196
      Location:127459
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    12. XM_036155840.1XP_036011733.1  liprin-alpha-2 isoform X27

      UniProtKB/Swiss-Prot
      Q6P1D2, Q8BN73, Q8BSS9
      Conserved Domains (4) summary
      cd09562
      Location:823893
      SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
      cd09565
      Location:9411006
      SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
      cd09568
      Location:10261097
      SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
      COG1196
      Location:127459
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    13. XM_006513780.4XP_006513843.1  liprin-alpha-2 isoform X10

      UniProtKB/Swiss-Prot
      Q6P1D2, Q8BN73, Q8BSS9
      Conserved Domains (4) summary
      cd09562
      Location:902972
      SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
      cd09565
      Location:10261091
      SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
      cd09568
      Location:11111182
      SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
      COG1196
      Location:201540
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    14. XM_017313985.2XP_017169474.1  liprin-alpha-2 isoform X14

      UniProtKB/Swiss-Prot
      Q6P1D2, Q8BN73, Q8BSS9
      Conserved Domains (4) summary
      cd09562
      Location:902972
      SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
      cd09565
      Location:10201085
      SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
      cd09568
      Location:11051176
      SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
      COG1196
      Location:201540
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    15. XM_017313980.2XP_017169469.1  liprin-alpha-2 isoform X11

      UniProtKB/Swiss-Prot
      Q6P1D2, Q8BN73, Q8BSS9
      Conserved Domains (4) summary
      cd09562
      Location:899969
      SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
      cd09565
      Location:10231088
      SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
      cd09568
      Location:11081179
      SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
      COG1196
      Location:201540
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    16. XM_017313987.2XP_017169476.1  liprin-alpha-2 isoform X17

      UniProtKB/Swiss-Prot
      Q6P1D2, Q8BN73, Q8BSS9
      Conserved Domains (5) summary
      cd09562
      Location:899969
      SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
      cd09565
      Location:10171082
      SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
      cd09568
      Location:11021173
      SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
      COG1196
      Location:201540
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      TIGR02168
      Location:39349
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    17. XM_036155834.1XP_036011727.1  liprin-alpha-2 isoform X18

      UniProtKB/Swiss-Prot
      Q6P1D2, Q8BN73, Q8BSS9
      Conserved Domains (4) summary
      cd09562
      Location:898968
      SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
      cd09565
      Location:10161081
      SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
      cd09568
      Location:11011172
      SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
      COG1196
      Location:201540
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    18. XM_030245142.1XP_030101002.1  liprin-alpha-2 isoform X22

      UniProtKB/Swiss-Prot
      Q6P1D2, Q8BN73, Q8BSS9
      Conserved Domains (4) summary
      cd09562
      Location:870940
      SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
      cd09565
      Location:9881053
      SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
      cd09568
      Location:10731144
      SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
      COG1196
      Location:168508
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    19. XM_006513782.4XP_006513845.1  liprin-alpha-2 isoform X16

      UniProtKB/Swiss-Prot
      Q6P1D2, Q8BN73, Q8BSS9
      Conserved Domains (5) summary
      cd09562
      Location:895965
      SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
      cd09565
      Location:10191084
      SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
      cd09568
      Location:11041175
      SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
      COG1196
      Location:201533
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      TIGR02168
      Location:39345
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    20. XM_006513777.5XP_006513840.1  liprin-alpha-2 isoform X6

      UniProtKB/Swiss-Prot
      Q6P1D2, Q8BN73, Q8BSS9
      Conserved Domains (4) summary
      cd09562
      Location:902972
      SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
      cd09565
      Location:10201085
      SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
      cd09568
      Location:11051176
      SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
      COG1196
      Location:201540
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    21. XM_030245138.1XP_030100998.1  liprin-alpha-2 isoform X9

      UniProtKB/Swiss-Prot
      Q6P1D2, Q8BN73, Q8BSS9
      Conserved Domains (4) summary
      cd09562
      Location:902972
      SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
      cd09565
      Location:10161081
      SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
      cd09568
      Location:11011172
      SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
      COG1196
      Location:201540
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    22. XM_006513775.4XP_006513838.1  liprin-alpha-2 isoform X3

      UniProtKB/Swiss-Prot
      Q6P1D2, Q8BN73, Q8BSS9
      Conserved Domains (4) summary
      cd09562
      Location:899969
      SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
      cd09565
      Location:10231088
      SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
      cd09568
      Location:11081179
      SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
      COG1196
      Location:201540
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    23. XM_006513778.5XP_006513841.1  liprin-alpha-2 isoform X7

      UniProtKB/Swiss-Prot
      Q6P1D2, Q8BN73, Q8BSS9
      Conserved Domains (5) summary
      cd09562
      Location:899969
      SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
      cd09565
      Location:10171082
      SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
      cd09568
      Location:11021173
      SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
      COG1196
      Location:201540
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      TIGR02168
      Location:39349
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    24. XM_017313972.2XP_017169461.1  liprin-alpha-2 isoform X2

      UniProtKB/Swiss-Prot
      Q6P1D2, Q8BN73, Q8BSS9
      Conserved Domains (4) summary
      cd09562
      Location:901971
      SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
      cd09565
      Location:10251090
      SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
      cd09568
      Location:11101181
      SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
      COG1196
      Location:201540
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    25. XM_017313977.3XP_017169466.1  liprin-alpha-2 isoform X8

      UniProtKB/Swiss-Prot
      Q6P1D2, Q8BN73, Q8BSS9
      Conserved Domains (5) summary
      cd09562
      Location:898968
      SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
      cd09565
      Location:10161081
      SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
      cd09568
      Location:11011172
      SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
      COG1196
      Location:201540
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      TIGR02168
      Location:39349
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    26. XM_036155832.1XP_036011725.1  liprin-alpha-2 isoform X13

      UniProtKB/Swiss-Prot
      Q6P1D2, Q8BN73, Q8BSS9
      Conserved Domains (4) summary
      cd09562
      Location:898968
      SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
      cd09565
      Location:10121077
      SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
      cd09568
      Location:10971168
      SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
      COG1196
      Location:201540
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    27. XM_036155833.1XP_036011726.1  liprin-alpha-2 isoform X15

      UniProtKB/Swiss-Prot
      Q6P1D2, Q8BN73, Q8BSS9
      Conserved Domains (4) summary
      cd09562
      Location:895965
      SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
      cd09565
      Location:10091074
      SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
      cd09568
      Location:10941165
      SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
      COG1196
      Location:201533
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    28. XM_017313974.2XP_017169463.1  liprin-alpha-2 isoform X5

      UniProtKB/Swiss-Prot
      Q6P1D2, Q8BN73, Q8BSS9
      Conserved Domains (4) summary
      cd09562
      Location:897967
      SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
      cd09565
      Location:10211086
      SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
      cd09568
      Location:11061177
      SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
      COG1196
      Location:201533
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    29. XM_017313981.3XP_017169470.1  liprin-alpha-2 isoform X12

      UniProtKB/Swiss-Prot
      Q6P1D2, Q8BN73, Q8BSS9
      Conserved Domains (5) summary
      cd09562
      Location:894964
      SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
      cd09565
      Location:10121077
      SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
      cd09568
      Location:10971168
      SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
      COG1196
      Location:201533
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      TIGR02168
      Location:39345
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    30. XM_030245140.1XP_030101000.1  liprin-alpha-2 isoform X20

      UniProtKB/Swiss-Prot
      Q6P1D2, Q8BN73, Q8BSS9
      Conserved Domains (4) summary
      cd09562
      Location:874944
      SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
      cd09565
      Location:9981063
      SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
      cd09568
      Location:10831154
      SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
      COG1196
      Location:168515
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    31. XM_030245141.1XP_030101001.1  liprin-alpha-2 isoform X21

      UniProtKB/Swiss-Prot
      Q6P1D2, Q8BN73, Q8BSS9
      Conserved Domains (4) summary
      cd09562
      Location:873943
      SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
      cd09565
      Location:9971062
      SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
      cd09568
      Location:10821153
      SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
      COG1196
      Location:168508
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    32. XM_036155831.1XP_036011724.1  liprin-alpha-2 isoform X5

      UniProtKB/Swiss-Prot
      Q6P1D2, Q8BN73, Q8BSS9
      Conserved Domains (4) summary
      cd09562
      Location:897967
      SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
      cd09565
      Location:10211086
      SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
      cd09568
      Location:11061177
      SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
      COG1196
      Location:201533
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    33. XM_036155829.1XP_036011722.1  liprin-alpha-2 isoform X1

      UniProtKB/Swiss-Prot
      Q6P1D2, Q8BN73, Q8BSS9
      Conserved Domains (4) summary
      cd09562
      Location:902972
      SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
      cd09565
      Location:10261091
      SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
      cd09568
      Location:11111182
      SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
      COG1196
      Location:201540
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    34. XM_036155842.1XP_036011735.1  liprin-alpha-2 isoform X29

      UniProtKB/Swiss-Prot
      Q6P1D2, Q8BN73, Q8BSS9
      Conserved Domains (4) summary
      cd09562
      Location:800870
      SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
      cd09565
      Location:924989
      SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
      cd09568
      Location:10091080
      SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
      COG1196
      Location:94441
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    35. XM_036155847.1XP_036011740.1  liprin-alpha-2 isoform X34

      UniProtKB/Swiss-Prot
      Q6P1D2, Q8BN73, Q8BSS9
      Conserved Domains (4) summary
      cd09562
      Location:800870
      SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
      cd09565
      Location:924989
      SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
      cd09568
      Location:10091080
      SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
      COG1196
      Location:94441
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    36. XM_036155846.1XP_036011739.1  liprin-alpha-2 isoform X33

      UniProtKB/Swiss-Prot
      Q6P1D2, Q8BN73, Q8BSS9
      Conserved Domains (4) summary
      cd09562
      Location:800870
      SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
      cd09565
      Location:918983
      SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
      cd09568
      Location:10031074
      SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
      COG1196
      Location:94441
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    37. XM_036155841.1XP_036011734.1  liprin-alpha-2 isoform X28

      UniProtKB/Swiss-Prot
      Q6P1D2, Q8BN73, Q8BSS9
      Conserved Domains (4) summary
      cd09562
      Location:802872
      SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
      cd09565
      Location:926991
      SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
      cd09568
      Location:10111082
      SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
      COG1196
      Location:94441
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    38. XM_036155844.1XP_036011737.1  liprin-alpha-2 isoform X31

      UniProtKB/Swiss-Prot
      Q6P1D2, Q8BN73, Q8BSS9
      Conserved Domains (4) summary
      cd09562
      Location:796866
      SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
      cd09565
      Location:920985
      SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
      cd09568
      Location:10051076
      SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
      COG1196
      Location:94434
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    39. XM_036155849.1XP_036011742.1  liprin-alpha-2 isoform X36

      UniProtKB/Swiss-Prot
      Q6P1D2, Q8BN73, Q8BSS9
      Conserved Domains (4) summary
      cd09562
      Location:796866
      SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
      cd09565
      Location:920985
      SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
      cd09568
      Location:10051076
      SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
      COG1196
      Location:94434
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    40. XM_036155843.1XP_036011736.1  liprin-alpha-2 isoform X30

      UniProtKB/Swiss-Prot
      Q6P1D2, Q8BN73, Q8BSS9
      Conserved Domains (4) summary
      cd09562
      Location:798868
      SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
      cd09565
      Location:922987
      SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
      cd09568
      Location:10071078
      SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
      COG1196
      Location:94434
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    41. XM_036155845.1XP_036011738.1  liprin-alpha-2 isoform X32

      UniProtKB/Swiss-Prot
      Q6P1D2, Q8BN73, Q8BSS9
      Conserved Domains (4) summary
      cd09562
      Location:795865
      SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
      cd09565
      Location:919984
      SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
      cd09568
      Location:10041075
      SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
      COG1196
      Location:94434
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    42. XM_036155850.1XP_036011743.1  liprin-alpha-2 isoform X37

      UniProtKB/Swiss-Prot
      Q6P1D2, Q8BN73, Q8BSS9
      Conserved Domains (4) summary
      cd09562
      Location:795865
      SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
      cd09565
      Location:919984
      SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
      cd09568
      Location:10041075
      SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
      COG1196
      Location:94434
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    43. XM_036155848.1XP_036011741.1  liprin-alpha-2 isoform X35

      UniProtKB/Swiss-Prot
      Q6P1D2, Q8BN73, Q8BSS9
      Conserved Domains (4) summary
      cd09562
      Location:795865
      SAM_liprin-alpha1,2,3,4_repeat1; SAM domain of liprin-alpha1,2,3,4 proteins repeat 1
      cd09565
      Location:913978
      SAM_liprin-alpha1,2,3,4_repeat2; SAM domain of liprin-alpha1,2,3,4 proteins repeat 2
      cd09568
      Location:9981069
      SAM_liprin-alpha1,2,3,4_repeat3; SAM domain of liprin-alpha1,2,3,4 proteins repeat 3
      COG1196
      Location:94434
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]