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    Rnf182 ring finger protein 182 [ Mus musculus (house mouse) ]

    Gene ID: 328234, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Rnf182provided by MGI
    Official Full Name
    ring finger protein 182provided by MGI
    Primary source
    MGI:MGI:3045355
    See related
    Ensembl:ENSMUSG00000044164 AllianceGenome:MGI:3045355
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    C630023L15Rik
    Summary
    Predicted to enable ubiquitin-protein transferase activity. Predicted to be involved in protein ubiquitination. Predicted to be located in membrane. Predicted to be active in cytoplasm. Is expressed in cortical plate; olfactory epithelium; rest of cerebellum mantle layer; and telencephalon marginal layer. Orthologous to human RNF182 (ring finger protein 182). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in CNS E18 (RPKM 7.8), whole brain E14.5 (RPKM 6.5) and 8 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Rnf182 in Genome Data Viewer
    Location:
    13 A4; 13 21.6 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 13 NC_000079.7 (43769051..43824422)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 13 NC_000079.6 (43615733..43670946)

    Chromosome 13 - NC_000079.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 32939 Neighboring gene mitochondrial calcium uniporter regulator 1 Neighboring gene STARR-seq mESC enhancer starr_34344 Neighboring gene STARR-seq mESC enhancer starr_34345 Neighboring gene predicted gene, 52070 Neighboring gene STARR-seq mESC enhancer starr_34346 Neighboring gene predicted gene, 20751

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development. Bedogni F, et al. Front Mol Neurosci, 2021. PMID 34321999, Free PMC Article
    2. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    3. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
    4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    General gene information

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    Homology

    Clone Names

    • MGC107143

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables ubiquitin-protein transferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables ubiquitin-protein transferase activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables ubiquitin-protein transferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein ubiquitination IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in protein ubiquitination IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in protein ubiquitination ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in protein ubiquitination ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    E3 ubiquitin-protein ligase RNF182
    Names
    RING-type E3 ubiquitin transferase RNF182
    NP_899027.1
    XP_006516996.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_183204.4 → NP_899027.1  E3 ubiquitin-protein ligase RNF182

      See identical proteins and their annotated locations for NP_899027.1

      Status: VALIDATED

      Source sequence(s)
      AC124171, AC124465
      Consensus CDS
      CCDS26480.1
      UniProtKB/Swiss-Prot
      Q8C432
      Related
      ENSMUSP00000062005.3, ENSMUST00000059986.3
      Conserved Domains (1) summary
      cd16555
      Location:19 → 69
      RING-HC_RNF182; RING finger, HC subclass, found in RING finger protein 182 (RNF182) and similar proteins

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000079.7 Reference GRCm39 C57BL/6J

      Range
      43769051..43824422
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006516933.5 → XP_006516996.1  E3 ubiquitin-protein ligase RNF182 isoform X1

      See identical proteins and their annotated locations for XP_006516996.1

      UniProtKB/Swiss-Prot
      Q8C432
      Conserved Domains (1) summary
      cd16555
      Location:19 → 69
      RING-HC_RNF182; RING finger, HC subclass, found in RING finger protein 182 (RNF182) and similar proteins
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8C432.1 GenPept UniProtKB/Swiss-Prot:Q8C432

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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