U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    SOA1 Soa1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854640, updated on 9-Dec-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    SOA1
    Official Full Name
    Soa1p
    Primary source
    SGD:S000001428
    Locus tag
    YIL166C
    See related
    AllianceGenome:SGD:S000001428; FungiDB:YIL166C; VEuPathDB:YIL166C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables organic acid transmembrane transporter activity; organic anion transmembrane transporter activity; and sulfate transmembrane transporter activity. Involved in several processes, including inorganic anion transmembrane transport; organic acid transport; and organic anion transport. Located in cell periphery and fungal-type vacuole. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 25; gout; porokeratosis; and sialuria. Orthologous to several human genes including SLC17A1 (solute carrier family 17 member 1); SLC17A2 (solute carrier family 17 member 2); and SLC17A3 (solute carrier family 17 member 3). [provided by Alliance of Genome Resources, Dec 2024]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See SOA1 in Genome Data Viewer
    Location:
    chromosome: IX
    Exon count:
    1
    Sequence:
    Chromosome: IX; NC_001141.2 (30938..32566, complement)

    Chromosome IX - NC_001141.2Genomic Context describing neighboring genes Neighboring gene Css1p Neighboring gene pseudo Neighboring gene uncharacterized protein Neighboring gene Nit1p

    Genomic regions, transcripts, and products

    Go to the top of the page Help
    Genomic Sequence:
    NC_001141.2

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Phylogenetic classification of the major superfamily of membrane transport facilitators, as deduced from yeast genome sequencing. Nelissen B, et al. FEBS Lett, 1995 Dec 18. PMID 8543057
    2. The Mechanisms of Thiosulfate Toxicity against Saccharomyces cerevisiae. Chen Z, et al. Antioxidants (Basel), 2021 Apr 22. PMID 33922196, Free PMC Article
    3. Major sulfonate transporter Soa1 in Saccharomyces cerevisiae and considerable substrate diversity in its fungal family. Holt S, et al. Nat Commun, 2017 Feb 6. PMID 28165463, Free PMC Article
    4. The genome-wide transcriptional responses of Saccharomyces cerevisiae grown on glucose in aerobic chemostat cultures limited for carbon, nitrogen, phosphorus, or sulfur. Boer VM, et al. J Biol Chem, 2003 Jan 31. PMID 12414795
    5. Tup1-Ssn6 and Swi-Snf remodelling activities influence long-range chromatin organization upstream of the yeast SUC2 gene. Fleming AB, et al. Nucleic Acids Res, 2007. PMID 17704134, Free PMC Article

    See all (21) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables organic acid transmembrane transporter activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables organic anion transmembrane transporter activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables sulfate transmembrane transporter activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables sulfur compound transmembrane transporter activity IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    enables transmembrane transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in modified amino acid transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in nitrogen compound transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in organic acid transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in organic acid transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in organic anion transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in sulfate transmembrane transport IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in sulfite transmembrane transport IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    involved_in sulfur compound transport IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in cell periphery HDA PubMed 
    located_in fungal-type vacuole HDA PubMed 
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    Soa1p
    NP_012100.1
    • Sulfonate and inorganic sulfur transporter; low affinity sulfate, high affinity sulfite, thiosulfite and major sulfonate transporter; functions as a an H+ symporter; similar to the allantoate permease (Dal5p) subfamily of the major facilitator superfamily; mRNA expression is elevated by sulfur limitation; non-essential gene

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001141.2 Reference assembly

      Range
      30938..32566 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001179514.1 → NP_012100.1  TPA: Soa1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_012100.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VVC1, P40445
      UniProtKB/TrEMBL
      A0A1D9C0Y0, A6ZVB2, B3LU12, C8ZAU7, G2WFY5, N1P1U7
      Conserved Domains (1) summary
      cd17327
      Location:76 → 496
      MFS_FEN2_like; Pantothenate transporter FEN2 and similar transporters of the Major Facilitator Superfamily
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P40445.1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Other Literature Sources
    Molecular Biology Databases
    Research Materials
    Tools