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    Ceacam18 CEA cell adhesion molecule 18 [ Mus musculus (house mouse) ]

    Gene ID: 72431, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Ceacam18provided by MGI
    Official Full Name
    CEA cell adhesion molecule 18provided by MGI
    Primary source
    MGI:MGI:1919681
    See related
    Ensembl:ENSMUSG00000030472 AllianceGenome:MGI:1919681
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    2010110O04Rik
    Summary
    Predicted to be located in membrane. Orthologous to human CEACAM18 (CEA cell adhesion molecule 18). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Biased expression in duodenum adult (RPKM 20.6), small intestine adult (RPKM 20.3) and 2 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Ceacam18 in Genome Data Viewer
    Location:
    7 B3; 7 28.25 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (43284094..43298719)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (43634617..43649295)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E9290 Neighboring gene zinc finger protein 719 Neighboring gene STARR-seq mESC enhancer starr_18778 Neighboring gene STARR-seq mESC enhancer starr_18779 Neighboring gene zinc finger protein 819 Neighboring gene sialic acid binding Ig-like lectin E Neighboring gene uncharacterized LOC118567526 Neighboring gene STARR-positive B cell enhancer ABC_E11351

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Identification of a novel group of evolutionarily conserved members within the rapidly diverging murine Cea family. Zebhauser R, et al. Genomics, 2005 Nov. PMID 16139472
    2. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    3. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
    4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 
    • Gene trapped (1) 

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    carcinoembryonic antigen-related cell adhesion molecule 18
    Names
    CEA-related cell adhesion molecule 1
    carcinoembryonic antigen-related cell adhesion molecule 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001419040.1 → NP_001405969.1  carcinoembryonic antigen-related cell adhesion molecule 18 isoform 2 precursor

      Status: VALIDATED

      Source sequence(s)
      AC151989, AC154108

    2. NM_028236.2 → NP_082512.1  carcinoembryonic antigen-related cell adhesion molecule 18 isoform 1 precursor

      See identical proteins and their annotated locations for NP_082512.1

      Status: VALIDATED

      Source sequence(s)
      AC151989, AC154108
      Consensus CDS
      CCDS21177.1
      UniProtKB/Swiss-Prot
      Q9D871
      Related
      ENSMUSP00000032663.9, ENSMUST00000032663.10
      Conserved Domains (2) summary
      smart00410
      Location:243 → 315
      IG_like; Immunoglobulin like
      cl11960
      Location:42 → 134
      Ig; Immunoglobulin domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      43284094..43298719
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017312326.1 → XP_017167815.1  carcinoembryonic antigen-related cell adhesion molecule 18 isoform X1

      Conserved Domains (2) summary
      cd05774
      Location:68 → 170
      Ig_CEACAM_D1; First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM)
      cl11960
      Location:283 → 338
      Ig; Immunoglobulin domain

    2. XM_017312327.1 → XP_017167816.1  carcinoembryonic antigen-related cell adhesion molecule 18 isoform X2

      Conserved Domains (2) summary
      cd05774
      Location:68 → 170
      Ig_CEACAM_D1; First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM)
      cl11960
      Location:192 → 247
      Ig; Immunoglobulin domain

    3. XM_017312328.1 → XP_017167817.1  carcinoembryonic antigen-related cell adhesion molecule 18 isoform X4

      Conserved Domains (1) summary
      cl11960
      Location:94 → 149
      Ig; Immunoglobulin domain
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9D871.1 GenPept UniProtKB/Swiss-Prot:Q9D871

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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