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    TFAM transcription factor A, mitochondrial [ Sus scrofa (pig) ]

    Gene ID: 397279, updated on 3-Dec-2024

    Summary

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    Official Symbol
    TFAMprovided by VGNC
    Official Full Name
    transcription factor A, mitochondrialprovided by VGNC
    Primary source
    VGNC:VGNC:109416
    See related
    Ensembl:ENSSSCG00000040185
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Sus scrofa
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Suina; Suidae; Sus
    Expression
    Ubiquitous expression in kidney (RPKM 17.2), spleen (RPKM 14.5) and 8 other tissues See more
    Orthologs
    human mouse all
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    Genomic context

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    See TFAM in Genome Data Viewer
    Location:
    chromosome: 14
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    106 current Sscrofa11.1 (GCF_000003025.6) 14 NC_010456.5 (92261713..92279731, complement)
    105 previous assembly Sscrofa10.2 (GCF_000003025.5) 14 NC_010456.4 (100777168..100778350)

    Chromosome 14 - NC_010456.5Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC110256691 Neighboring gene 60S ribosomal protein L37a Neighboring gene ubiquitin conjugating enzyme E2 D1 Neighboring gene CDGSH iron sulfur domain 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Transcriptome data used for gene annotation
    • Description: Nine kinds of tissues and a mixture of multiple tissues were sequenced for genome annotation
    • BioProject: PRJNA311523
    • Publication: PMID 27646534
    • Analysis date: Thu Dec 14 17:10:49 2017

    Bibliography

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    Related articles in PubMed

    1. Expression of mitochondrial transcription factor A (TFAM) during porcine gametogenesis and preimplantation embryo development. Antelman J, et al. J Cell Physiol, 2008 Nov. PMID 18636550
    2. PEDE (Pig EST Data Explorer) has been expanded into Pig Expression Data Explorer, including 10 147 porcine full-length cDNA sequences. Uenishi H, et al. Nucleic Acids Res, 2007 Jan. PMID 17145712, Free PMC Article
    3. PEDE (Pig EST Data Explorer): construction of a database for ESTs derived from porcine full-length cDNA libraries. Uenishi H, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681463, Free PMC Article
    4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. TFAM may exert a critical role in porcine gametogenesis and preimplantation embryo development.
      Title: Expression of mitochondrial transcription factor A (TFAM) during porcine gametogenesis and preimplantation embryo development.
    Submit: New GeneRIF Correction

    Pathways from PubChem

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    General gene information

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    Markers

    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables transcription cis-regulatory region binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    transcription factor A, mitochondrial
    Names
    mitochondrial transcription factor A
    mtTFA

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001130211.1 → NP_001123683.1  transcription factor A, mitochondrial precursor

      See identical proteins and their annotated locations for NP_001123683.1

      Status: PROVISIONAL

      Source sequence(s)
      AY923074
      UniProtKB/Swiss-Prot
      Q5D144
      UniProtKB/TrEMBL
      A0A8D0JZU8
      Related
      ENSSSCP00000042490.1, ENSSSCT00000046982.2
      Conserved Domains (2) summary
      cd01390
      Location:155 → 216
      HMGB-UBF_HMG-box; HMGB-UBF_HMG-box, class II and III members of the HMG-box superfamily of DNA-binding proteins. These proteins bind the minor groove of DNA in a non-sequence specific fashion and contain two or more tandem HMG boxes. Class II members include non-histone ...
      pfam00505
      Location:50 → 114
      HMG_box; HMG (high mobility group) box

    RefSeqs of Annotated Genomes: Sus scrofa Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Sscrofa11.1 Primary Assembly

    Genomic

    1. NC_010456.5 Reference Sscrofa11.1 Primary Assembly

      Range
      92261713..92279731 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q5D144.1 GenPept UniProtKB/Swiss-Prot:Q5D144

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