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    Phip pleckstrin homology domain interacting protein [ Castor canadensis (American beaver) ]

    Gene ID: 109699237, updated on 14-Mar-2024

    Summary

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    Gene symbol
    Phip
    Gene description
    pleckstrin homology domain interacting protein
    See related
    Ensembl:ENSCCNG00000019824
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Castor canadensis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Castorimorpha; Castoridae; Castor
    Orthologs
    human mouse all
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    Genomic context

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    See Phip in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    42
    Annotation release Status Assembly Chr Location
    100 current C.can genome v1.0 (GCF_001984765.1) Unplaced Scaffold NW_017872485.1 (428419..540162, complement)

    NW_017872485.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 35 member E1 pseudogene Neighboring gene interleukin 1 receptor associated kinase 1 binding protein 1 Neighboring gene high mobility group nucleosomal binding domain 3 Neighboring gene lebercilin LCA5

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_017872485.1 Unplaced Scaffold Reference C.can genome v1.0

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Process Evidence Code Pubs
    involved_in cytoskeleton organization IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of cell shape IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    involved_in regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    PH-interacting protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: Castor canadensis Annotation Release 100 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference C.can genome v1.0

    Genomic

    1. NW_017872485.1 Reference C.can genome v1.0

      Range
      428419..540162 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_020183864.1 → XP_020039453.1  PH-interacting protein isoform X2

      UniProtKB/TrEMBL
      A0A8B7W6B5
      Conserved Domains (4) summary
      cd05496
      Location:1315 → 1433
      Bromo_WDR9_II; Bromodomain; WDR9 repeat II_like subfamily. WDR9 is a human gene located in the Down Syndrome critical region-2 of chromosome 21. It encodes for a nuclear protein containing WD40 repeats and two bromodomains, which may function as a transcriptional ...
      cd05529
      Location:1147 → 1262
      Bromo_WDR9_I_like; Bromodomain; WDR9 repeat I_like subfamily. WDR9 is a human gene located in the Down Syndrome critical region-2 of chromosome 21. It encodes for a nuclear protein containing WD40 repeats and two bromodomains, which may function as a transcriptional ...
      cd00200
      Location:175 → 495
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:186 → 223
      7WD40; WD40 repeat [structural motif]

    2. XM_020183863.1 → XP_020039452.1  PH-interacting protein isoform X1

      UniProtKB/TrEMBL
      A0A8B7W666
      Conserved Domains (4) summary
      cd05496
      Location:1316 → 1434
      Bromo_WDR9_II; Bromodomain; WDR9 repeat II_like subfamily. WDR9 is a human gene located in the Down Syndrome critical region-2 of chromosome 21. It encodes for a nuclear protein containing WD40 repeats and two bromodomains, which may function as a transcriptional ...
      cd05529
      Location:1148 → 1263
      Bromo_WDR9_I_like; Bromodomain; WDR9 repeat I_like subfamily. WDR9 is a human gene located in the Down Syndrome critical region-2 of chromosome 21. It encodes for a nuclear protein containing WD40 repeats and two bromodomains, which may function as a transcriptional ...
      cd00200
      Location:175 → 495
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:186 → 223
      7WD40; WD40 repeat [structural motif]

    3. XM_020183866.1 → XP_020039455.1  PH-interacting protein isoform X4

      UniProtKB/TrEMBL
      A0A8B7WBN6
      Conserved Domains (4) summary
      cd05496
      Location:1315 → 1433
      Bromo_WDR9_II; Bromodomain; WDR9 repeat II_like subfamily. WDR9 is a human gene located in the Down Syndrome critical region-2 of chromosome 21. It encodes for a nuclear protein containing WD40 repeats and two bromodomains, which may function as a transcriptional ...
      cd05529
      Location:1147 → 1262
      Bromo_WDR9_I_like; Bromodomain; WDR9 repeat I_like subfamily. WDR9 is a human gene located in the Down Syndrome critical region-2 of chromosome 21. It encodes for a nuclear protein containing WD40 repeats and two bromodomains, which may function as a transcriptional ...
      cd00200
      Location:175 → 495
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:186 → 223
      7WD40; WD40 repeat [structural motif]

    4. XM_020183865.1 → XP_020039454.1  PH-interacting protein isoform X3

      UniProtKB/TrEMBL
      A0A250Y864
      Related
      ENSCCNP00000019780.1, ENSCCNT00000025610.1
      Conserved Domains (4) summary
      cd05496
      Location:1316 → 1434
      Bromo_WDR9_II; Bromodomain; WDR9 repeat II_like subfamily. WDR9 is a human gene located in the Down Syndrome critical region-2 of chromosome 21. It encodes for a nuclear protein containing WD40 repeats and two bromodomains, which may function as a transcriptional ...
      cd05529
      Location:1148 → 1263
      Bromo_WDR9_I_like; Bromodomain; WDR9 repeat I_like subfamily. WDR9 is a human gene located in the Down Syndrome critical region-2 of chromosome 21. It encodes for a nuclear protein containing WD40 repeats and two bromodomains, which may function as a transcriptional ...
      cd00200
      Location:175 → 495
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:186 → 223
      7WD40; WD40 repeat [structural motif]

    5. XM_020183867.1 → XP_020039456.1  PH-interacting protein isoform X5

      UniProtKB/TrEMBL
      A0A8B7W5M0
      Conserved Domains (4) summary
      cd05496
      Location:1316 → 1434
      Bromo_WDR9_II; Bromodomain; WDR9 repeat II_like subfamily. WDR9 is a human gene located in the Down Syndrome critical region-2 of chromosome 21. It encodes for a nuclear protein containing WD40 repeats and two bromodomains, which may function as a transcriptional ...
      cd05529
      Location:1148 → 1263
      Bromo_WDR9_I_like; Bromodomain; WDR9 repeat I_like subfamily. WDR9 is a human gene located in the Down Syndrome critical region-2 of chromosome 21. It encodes for a nuclear protein containing WD40 repeats and two bromodomains, which may function as a transcriptional ...
      cd00200
      Location:175 → 495
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:186 → 223
      7WD40; WD40 repeat [structural motif]
    Nucleotide Protein
    Heading Accession and Version

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