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    CG40006 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 3355123, updated on 9-Dec-2024

    Summary

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    Official Symbol
    CG40006provided by FlyBase
    Official Full Name
    uncharacterized proteinprovided by FlyBase
    Primary source
    FLYBASE:FBgn0058006
    Locus tag
    Dmel_CG40006
    See related
    AllianceGenome:FB:FBgn0058006
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    BcDNA:RE68569; Dmel\CG40006
    Summary
    Predicted to enable scavenger receptor activity. Predicted to be active in membrane. Is expressed in embryonic/larval garland cell and embryonic/larval salivary gland. Human ortholog(s) of this gene implicated in progressive myoclonus epilepsy 4. Orthologous to human SCARB2 (scavenger receptor class B member 2). [provided by Alliance of Genome Resources, Dec 2024]
    Orthologs
    all
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    Genomic context

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    See CG40006 in Genome Data Viewer
    Location:
    40F7-40F7; 2-54 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 2L NT_033779.5 (22622417..22756349, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 2L NT_033779.4 (22515149..22649081, complement)

    Chromosome 2L - NT_033779.5Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Sarcolemma associated protein Neighboring gene long non-coding RNA:CR43927 Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR43266

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. HP1a targets the Drosophila KDM4A demethylase to a subset of heterochromatic genes to regulate H3K36me3 levels. Lin CH, et al. PLoS One, 2012. PMID 22761891, Free PMC Article
    2. Expression of the Scavenger Receptor Class B type I (SR-BI) family in Drosophila melanogaster. Herboso L, et al. Int J Dev Biol, 2011. PMID 21948708
    3. Evolution of heterochromatic genes of Drosophila. Yasuhara JC, et al. Proc Natl Acad Sci U S A, 2005 Aug 2. PMID 16033869, Free PMC Article
    4. Tau promotes neurodegeneration through global chromatin relaxation. Frost B, et al. Nat Neurosci, 2014 Mar. PMID 24464041, Free PMC Article
    5. The SNMP/CD36 gene family in Diptera, Hymenoptera and Coleoptera: Drosophila melanogaster, D. pseudoobscura, Anopheles gambiae, Aedes aegypti, Apis mellifera, and Tribolium castaneum. Nichols Z, et al. Insect Biochem Mol Biol, 2008 Apr. PMID 18342246

    See all (39) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    mobile_element

    • Loc: c22630952-22629826 mobile_element_type = transposon:1360{}6308

    Gene Ontology Provided by FlyBase

    Function Evidence Code Pubs
    enables scavenger receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    uncharacterized protein
    Names
    CG40006-PA

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_033779.5 Reference assembly

      Range
      22622417..22756349 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001042936.1 → NP_001036401.1  uncharacterized protein Dmel_CG40006 [Drosophila melanogaster]

      See identical proteins and their annotated locations for NP_001036401.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q8SYC3
      Conserved Domains (1) summary
      pfam01130
      Location:91 → 545
      CD36; CD36 family
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8SYC3 Q8SYC3

    Gene LinkOut

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