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    Prr19 proline rich 19 [ Mus musculus (house mouse) ]

    Gene ID: 623131, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Prr19provided by MGI
    Official Full Name
    proline rich 19provided by MGI
    Primary source
    MGI:MGI:3648539
    See related
    Ensembl:ENSMUSG00000058741 AllianceGenome:MGI:3648539
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    EG623131
    Summary
    Predicted to be involved in meiotic cell cycle. Located in chromosome and nucleus. Orthologous to human PRR19 (proline rich 19). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Restricted expression toward testis adult (RPKM 30.9) See more
    Orthologs
    human all
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    Genomic context

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    See Prr19 in Genome Data Viewer
    Location:
    7 A3; 7 13.74 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (25000784..25003565)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (25301359..25304140)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_18299 Neighboring gene predicted gene, 45974 Neighboring gene STARR-positive B cell enhancer ABC_E8154 Neighboring gene capicua transcriptional repressor Neighboring gene STARR-positive B cell enhancer ABC_E2226 Neighboring gene platelet-activating factor acetylhydrolase, isoform 1b, subunit 3 Neighboring gene STARR-seq mESC enhancer starr_18300 Neighboring gene transmembrane protein 145 Neighboring gene multiple EGF-like-domains 8

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Proline-rich protein PRR19 functions with cyclin-like CNTD1 to promote meiotic crossing over in mouse. Bondarieva A, et al. Nat Commun, 2020 Jun 18. PMID 32555348, Free PMC Article
    2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in meiotic cell cycle IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in chromosome IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    proline-rich protein 19

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001081294.1 → NP_001074763.1  proline-rich protein 19

      See identical proteins and their annotated locations for NP_001074763.1

      Status: PROVISIONAL

      Source sequence(s)
      AC156992
      Consensus CDS
      CCDS52147.1
      UniProtKB/Swiss-Prot
      B2RW88
      Related
      ENSMUSP00000104047.2, ENSMUST00000080288.5
      Conserved Domains (1) summary
      pfam15455
      Location:1 → 366
      Pro-rich_19; Proline-rich 19

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      25000784..25003565
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017322433.1 → XP_017177922.1  proline-rich protein 19 isoform X1

      UniProtKB/Swiss-Prot
      B2RW88
      Conserved Domains (1) summary
      pfam15455
      Location:1 → 366
      Pro-rich_19; Proline-rich 19

    2. XM_006540262.1 → XP_006540325.1  proline-rich protein 19 isoform X1

      See identical proteins and their annotated locations for XP_006540325.1

      UniProtKB/Swiss-Prot
      B2RW88
      Conserved Domains (1) summary
      pfam15455
      Location:1 → 366
      Pro-rich_19; Proline-rich 19
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    B2RW88.1 GenPept UniProtKB/Swiss-Prot:B2RW88

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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