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    PF3D7_1034900 methionine--tRNA ligase [ Plasmodium falciparum 3D7 ]

    Gene ID: 810497, updated on 12-Sep-2024

    Summary

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    Gene symbol
    PF3D7_1034900
    Gene description
    methionine--tRNA ligase
    Locus tag
    PF3D7_1034900
    See related
    PlasmoDB:PF3D7_1034900; VEuPathDB:PF3D7_1034900
    Gene type
    protein coding
    RNA name
    methionine--tRNA ligase
    RefSeq status
    PROVISIONAL
    Organism
    Plasmodium falciparum 3D7 (isolate: 3D7)
    Lineage
    Eukaryota; Sar; Alveolata; Apicomplexa; Aconoidasida; Haemosporida; Plasmodiidae; Plasmodium; Plasmodium (Laverania)
    Orthologs
    all
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    Genomic context

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    See PF3D7_1034900 in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    1
    Sequence:
    Chromosome: 10; NC_037281.1 (1383450..1386119)

    Chromosome 10 - NC_037281.1Genomic Context describing neighboring genes Neighboring gene ADP-ribosylation factor, putative Neighboring gene conserved protein, unknown function Neighboring gene U2 snRNA/tRNA pseudouridine synthase, putative Neighboring gene probable protein, unknown function

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_037281.1

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Inhibition of protein synthesis and malaria parasite development by drug targeting of methionyl-tRNA synthetases. Hussain T, et al. Antimicrob Agents Chemother, 2015 Apr. PMID 25583729, Free PMC Article
    2. Identification of Plasmodium falciparum nuclear proteins by mass spectrometry and proposed protein annotation. Briquet S, et al. PLoS One, 2018. PMID 30379851, Free PMC Article
    3. Organellar proteomics reveals hundreds of novel nuclear proteins in the malaria parasite Plasmodium falciparum. Oehring SC, et al. Genome Biol, 2012 Nov 26. PMID 23181666, Free PMC Article
    4. Genome sequence of the human malaria parasite Plasmodium falciparum. Gardner MJ, et al. Nature, 2002 Oct 3. PMID 12368864, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by GeneDB

    Function Evidence Code Pubs
    enables methionine-tRNA ligase activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within methionyl-tRNA aminoacylation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in nucleus HDA PubMed 

    General protein information

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    Preferred Names
    methionine--tRNA ligase
    XP_001347624.1

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_037281.1 Reference assembly

      Range
      1383450..1386119
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_001347588.1 → XP_001347624.1  methionine--tRNA ligase [Plasmodium falciparum 3D7]

      See identical proteins and their annotated locations for XP_001347624.1

      Status: PROVISIONAL

      UniProtKB/TrEMBL
      A0A024VQH5, A0A024X6J0, Q8IJ60, W4IFP4, W4J2M5, W7K331
      Conserved Domains (1) summary
      PRK11893
      Location:223 → 724
      PRK11893; methionyl-tRNA synthetase; Reviewed
    Nucleotide Protein
    Heading Accession and Version

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