Eef1akmt4 EEF1A lysine methyltransferase 4 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Eef1akmt4provided by MGI
Official Full Name: EEF1A lysine methyltransferase 4provided by MGI
Primary source: MGI:MGI:5903914
See related: Ensembl:ENSMUSG00000115219 AllianceGenome:MGI:5903914
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary: This gene encodes a member of the lysine-specific methyltransferase (KMT) family. The encoded enzyme catalyzes the methylation of lysine-36 of the eukaryotic translation elongation factor 1 alpha. Methylation by this enzyme may affect endoplasmic reticulum-related processes. [provided by RefSeq, Jul 2017]
Annotation information: Note: This gene was annotated as Ece2 (GeneID:107522) until recently in Annotation Release 106. It is now annotated as an independent gene adjacent to GeneID:107522 based on a published report in a human study (PMID:28520920). [12 Jul 2017]
Orthologs: human all
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Genomic context

Location:: 16 A3; 16

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	16	NC_000082.7 (20430351..20437619)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	16	NC_000082.6 (20611601..20618869)

Chromosome 16 - NC_000082.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Readthrough Eef1ece2

Readthrough gene: Eef1ece2, Included gene: Ece2

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables methyltransferase activity	ISO Inferred from Sequence Orthology more info
enables methyltransferase activity	ISS Inferred from Sequence or Structural Similarity more info
enables protein-lysine N-methyltransferase activity	ISO Inferred from Sequence Orthology more info
enables protein-lysine N-methyltransferase activity	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
involved_in methylation	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: EEF1A lysine methyltransferase 4

Names: eukaryotic translation elongation factor 1 alpha lysine specific methyltransferase 4

NP_079738.2

EC 2.1.1.-

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.