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    Dynap dynactin associated protein [ Mus musculus (house mouse) ]

    Gene ID: 75577, updated on 9-Dec-2024

    Summary

    Official Symbol
    Dynapprovided by MGI
    Official Full Name
    dynactin associated proteinprovided by MGI
    Primary source
    MGI:MGI:1922827
    See related
    Ensembl:ENSMUSG00000024512 AllianceGenome:MGI:1922827
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    2310002L13Rik
    Summary
    Predicted to be involved in several processes, including activation of protein kinase B activity; cellular response to ergosterol; and positive regulation of cell population proliferation. Predicted to be active in Golgi apparatus and plasma membrane. Orthologous to human DYNAP (dynactin associated protein). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

    See Dynap in Genome Data Viewer
    Location:
    18 E2; 18 44.21 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 18 NC_000084.7 (70373500..70377655, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 18 NC_000084.6 (70240429..70244584, complement)

    Chromosome 18 - NC_000084.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_44955 Neighboring gene coiled-coil domain containing 68 Neighboring gene crumbs homolog 1 pseudogene Neighboring gene RAB27B, member RAS oncogene family Neighboring gene STARR-seq mESC enhancer starr_44957 Neighboring gene predicted gene, 41770 Neighboring gene STARR-seq mESC enhancer starr_44958 Neighboring gene STARR-seq mESC enhancer starr_44960 Neighboring gene dynactin associated protein like 1 Neighboring gene STARR-seq mESC enhancer starr_44961 Neighboring gene STARR-seq mESC enhancer starr_44962 Neighboring gene predicted gene, 31620

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    General gene information

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in activation of protein kinase B activity ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in cellular response to ergosterol ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of cell population proliferation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in positive regulation of cell population proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of apoptotic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in regulation of apoptotic process ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    dynactin-associated protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_029346.1NP_083622.1  dynactin-associated protein

      See identical proteins and their annotated locations for NP_083622.1

      Status: VALIDATED

      Source sequence(s)
      AC124764, AK009098
      Consensus CDS
      CCDS50316.1
      UniProtKB/TrEMBL
      G8CXX7, Q9D7M5
      Related
      ENSMUSP00000025390.3, ENSMUST00000025390.4
      Conserved Domains (1) summary
      pfam15675
      Location:5179
      CLLAC; CLLAC-motif containing domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000084.7 Reference GRCm39 C57BL/6J

      Range
      70373500..70377655 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)