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    Nrp1 neuropilin 1 [ Mus musculus (house mouse) ]

    Gene ID: 18186, updated on 27-Nov-2024

    Summary

    Official Symbol
    Nrp1provided by MGI
    Official Full Name
    neuropilin 1provided by MGI
    Primary source
    MGI:MGI:106206
    See related
    Ensembl:ENSMUSG00000025810 AllianceGenome:MGI:106206
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Nrp; NP-1; Npn1; NPN-1; C530029I03
    Summary
    Enables protein kinase binding activity; transmembrane signaling receptor activity; and vascular endothelial growth factor binding activity. Involved in several processes, including cell surface receptor signaling pathway; nervous system development; and vasculature development. Acts upstream of or within several processes, including circulatory system development; dichotomous subdivision of terminal units involved in salivary gland branching; and nervous system development. Located in several cellular components, including endosome; focal adhesion; and neurofilament. Is active in glutamatergic synapse and postsynaptic membrane. Is expressed in several structures, including cardiovascular system; jaw; lung; nervous system; and sensory organ. Used to study retinal vein occlusion. Human ortholog(s) of this gene implicated in lung non-small cell carcinoma and tetralogy of Fallot. Orthologous to human NRP1 (neuropilin 1). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Broad expression in lung adult (RPKM 39.3), subcutaneous fat pad adult (RPKM 21.5) and 24 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Nrp1 in Genome Data Viewer
    Location:
    8 E2; 8 75.78 cM
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (129085553..129231957)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (128358591..128505476)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 32590 Neighboring gene STARR-seq mESC enhancer starr_23094 Neighboring gene STARR-seq mESC enhancer starr_23095 Neighboring gene STARR-seq mESC enhancer starr_23096 Neighboring gene STARR-seq mESC enhancer starr_23098 Neighboring gene STARR-seq mESC enhancer starr_23099 Neighboring gene STARR-seq mESC enhancer starr_23100 Neighboring gene RIKEN cDNA A930035F09 gene Neighboring gene STARR-seq mESC enhancer starr_23101 Neighboring gene predicted gene, 53472 Neighboring gene microRNA 21c Neighboring gene CapStarr-seq enhancer MGSCv37_chr8:130882383-130882492 Neighboring gene microRNA 1903 Neighboring gene STARR-positive B cell enhancer ABC_E5052 Neighboring gene STARR-seq mESC enhancer starr_23102 Neighboring gene predicted gene, 32643 Neighboring gene predicted gene, 26002 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables GTPase activator activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables GTPase activator activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables growth factor binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables growth factor binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables heparin binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein kinase binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables semaphorin receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables semaphorin receptor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables semaphorin receptor activity IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    enables semaphorin receptor activity IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables semaphorin receptor activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables vascular endothelial growth factor binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables vascular endothelial growth factor binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables vascular endothelial growth factor binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables vascular endothelial growth factor receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables vascular endothelial growth factor receptor activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in VEGF-activated neuropilin signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in VEGF-activated neuropilin signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in angiogenesis IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    acts_upstream_of_or_within angiogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in angiogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in angiogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in angiogenesis involved in coronary vascular morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in artery morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of axon extension IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    acts_upstream_of axon extension involved in axon guidance IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in axon extension involved in axon guidance IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in axon guidance IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within axon guidance IDA
    Inferred from Direct Assay
    more info
    PubMed 
    acts_upstream_of_or_within axon guidance IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within axonal fasciculation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in axonogenesis involved in innervation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in basal dendrite arborization IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in basal dendrite development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within blood vessel endothelial cell migration IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within branching involved in blood vessel morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in branching involved in blood vessel morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in branchiomotor neuron axon guidance IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    NOT involved_in cardiac neural crest cell migration involved in outflow tract morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in cell migration involved in coronary vasculogenesis IC
    Inferred by Curator
    more info
    PubMed 
    involved_in cell migration involved in sprouting angiogenesis IC
    Inferred by Curator
    more info
    PubMed 
    involved_in cell migration involved in sprouting angiogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in cellular response to hepatocyte growth factor stimulus IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in cellular response to hepatocyte growth factor stimulus ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in cellular response to vascular endothelial growth factor stimulus IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in commissural neuron axon guidance IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in coronary artery morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within dendrite development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within dichotomous subdivision of terminal units involved in salivary gland branching IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    acts_upstream_of_or_within dichotomous subdivision of terminal units involved in salivary gland branching IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in dorsal root ganglion morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in endothelial cell chemotaxis IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in endothelial cell chemotaxis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in endothelial cell migration IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in facial nerve structural organization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in facioacoustic ganglion development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in gonadotrophin-releasing hormone neuronal migration to the hypothalamus IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within heart development IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in hepatocyte growth factor receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in hepatocyte growth factor receptor signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in integrin-mediated signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in integrin-mediated signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in motor neuron axon guidance IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in motor neuron migration IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within negative regulation of axon extension IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    acts_upstream_of_or_within negative regulation of axon extension involved in axon guidance IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in negative regulation of axon extension involved in axon guidance ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of extrinsic apoptotic signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in negative regulation of neuron apoptotic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in neural crest cell migration IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in neural crest cell migration involved in autonomic nervous system development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in neuron development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in neuron migration IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in neuropilin signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in neuropilin signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in otic placode development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in outflow tract septum morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in platelet-derived growth factor receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in platelet-derived growth factor receptor signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive chemotaxis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of ERK1 and ERK2 cascade IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of angiogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of axon extension involved in axon guidance IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of cell migration involved in sprouting angiogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of endothelial cell migration IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in positive regulation of endothelial cell migration IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of endothelial cell migration ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of filopodium assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in positive regulation of filopodium assembly IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of filopodium assembly ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of focal adhesion assembly IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in positive regulation of focal adhesion assembly ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of peptidyl-tyrosine phosphorylation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of phosphorylation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of platelet-derived growth factor receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in positive regulation of platelet-derived growth factor receptor signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of smooth muscle cell chemotaxis IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in positive regulation of smooth muscle cell chemotaxis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of stress fiber assembly IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in positive regulation of stress fiber assembly ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of substrate adhesion-dependent cell spreading IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in positive regulation of substrate adhesion-dependent cell spreading ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of vascular associated smooth muscle cell migration IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in positive regulation of vascular associated smooth muscle cell migration ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in postsynapse organization IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in postsynapse organization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in protein localization to early endosome IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in regulation of Cdc42 protein signal transduction IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in regulation of Cdc42 protein signal transduction ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within regulation of axon extension involved in axon guidance IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in regulation of vascular endothelial growth factor receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in renal artery morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in response to wounding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within retina vasculature development in camera-type eye IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in retina vasculature morphogenesis in camera-type eye IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in retinal ganglion cell axon guidance IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within semaphorin-plexin signaling pathway IDA
    Inferred from Direct Assay
    more info
    PubMed 
    acts_upstream_of_or_within semaphorin-plexin signaling pathway IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in semaphorin-plexin signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in sensory neuron axon guidance IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in sprouting angiogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in sprouting angiogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in substrate-dependent cell migration, cell extension IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of substrate-dependent cell migration, cell extension ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in symbiont entry into host cell IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in symbiont entry into host cell ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in sympathetic ganglion development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within sympathetic nervous system development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in sympathetic neuron projection extension IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in sympathetic neuron projection guidance IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in trigeminal ganglion development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within trigeminal nerve morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in trigeminal nerve structural organization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in vascular endothelial growth factor receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within vascular endothelial growth factor receptor signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in vascular endothelial growth factor receptor signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in vascular endothelial growth factor receptor signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in vasculogenesis IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in ventral trunk neural crest cell migration IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in vestibulocochlear nerve structural organization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in wound healing IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in wound healing ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    is_active_in axon IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in axon IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in axon ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cell surface IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cell surface ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in early endosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in focal adhesion IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in focal adhesion IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in focal adhesion ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in glutamatergic synapse IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in glutamatergic synapse IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    located_in growth cone IEA
    Inferred from Electronic Annotation
    more info
     
    located_in growth cone ISO
    Inferred from Sequence Orthology
    more info
     
    located_in mitochondrial membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in neurofilament IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in neuron projection IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in neuronal cell body IEA
    Inferred from Electronic Annotation
    more info
     
    located_in neuronal cell body ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in plasma membrane TAS
    Traceable Author Statement
    more info
     
    is_active_in postsynaptic membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in sorting endosome IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    neuropilin-1
    Names
    A5 protein
    Neuropilin-1 precursor (A5 protein)
    transmembrane receptor

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001358959.2NP_001345888.1  neuropilin-1 isoform 2 precursor

      Status: VALIDATED

      Source sequence(s)
      AC102856, AC139349
      UniProtKB/TrEMBL
      Q3UQY7
      Conserved Domains (4) summary
      cd00041
      Location:27140
      CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
      cd00057
      Location:277423
      FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.
      pfam00629
      Location:643803
      MAM; MAM domain, meprin/A5/mu
      pfam11980
      Location:838916
      DUF3481; C-terminal domain of neuropilin glycoprotein
    2. NM_001358960.2NP_001345889.1  neuropilin-1 isoform 3 precursor

      Status: VALIDATED

      Source sequence(s)
      AC102856, AC139349
      UniProtKB/TrEMBL
      Q3UQY7
      Conserved Domains (4) summary
      cd00041
      Location:27140
      CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
      cd00057
      Location:277423
      FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.
      pfam00629
      Location:650810
      MAM; MAM domain, meprin/A5/mu
      pfam11980
      Location:828906
      DUF3481; C-terminal domain of neuropilin glycoprotein
    3. NM_001424858.1NP_001411787.1  neuropilin-1 isoform 4 precursor

      Status: VALIDATED

      Source sequence(s)
      AC102856, AC139349
    4. NM_001424859.1NP_001411788.1  neuropilin-1 isoform 5 precursor

      Status: VALIDATED

      Source sequence(s)
      AC102856, AC139349
    5. NM_008737.3NP_032763.2  neuropilin-1 isoform 1 precursor

      See identical proteins and their annotated locations for NP_032763.2

      Status: VALIDATED

      Source sequence(s)
      AC102856, AC139349
      Consensus CDS
      CCDS22790.1
      UniProtKB/Swiss-Prot
      P97333, Q6PAR3
      UniProtKB/TrEMBL
      Q3UQY7
      Related
      ENSMUSP00000026917.9, ENSMUST00000026917.10
      Conserved Domains (4) summary
      cd00041
      Location:27140
      CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
      cd00057
      Location:277423
      FA58C; Coagulation factor 5/8 C-terminal domain, discoidin domain; Cell surface-attached carbohydrate-binding domain, present in eukaryotes and assumed to have horizontally transferred to eubacterial genomes.
      pfam00629
      Location:650810
      MAM; MAM domain, meprin/A5/mu
      pfam11980
      Location:845923
      DUF3481; C-terminal domain of neuropilin glycoprotein

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      129085553..129231957
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)