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    Ttc23l tetratricopeptide repeat domain 23-like [ Mus musculus (house mouse) ]

    Gene ID: 75777, updated on 27-Nov-2024

    Summary

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    Official Symbol
    Ttc23lprovided by MGI
    Official Full Name
    tetratricopeptide repeat domain 23-likeprovided by MGI
    Primary source
    MGI:MGI:1923027
    See related
    Ensembl:ENSMUSG00000022249 AllianceGenome:MGI:1923027
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    4930401A09Rik
    Summary
    Predicted to be located in cytoplasm; microtubule cytoskeleton; and midbody. Orthologous to human TTC23L (tetratricopeptide repeat domain 23 like). [provided by Alliance of Genome Resources, Nov 2024]
    Expression
    Restricted expression toward testis adult (RPKM 20.6) See more
    Orthologs
    human all
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    Genomic context

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    See Ttc23l in Genome Data Viewer
    Location:
    15 A1; 15 5.35 cM
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (10497309..10559006, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (10497223..10558775, complement)

    Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene DnaJ heat shock protein family (Hsp40) member C21 Neighboring gene STARR-positive B cell enhancer ABC_E9414 Neighboring gene STARR-seq mESC enhancer starr_37954 Neighboring gene BRX1, biogenesis of ribosomes Neighboring gene RAD1 checkpoint DNA exonuclease Neighboring gene STARR-seq mESC enhancer starr_37955 Neighboring gene glyceraldehyde-3-phosphate dehydrogenase pseudogene Neighboring gene retinoic acid induced 14 Neighboring gene predicted gene 10389

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
    2. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
    3. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    4. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article
    5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    located_in centrosome IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in midbody IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in spindle IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    tetratricopeptide repeat protein 23-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001374772.1 → NP_001361701.1  tetratricopeptide repeat protein 23-like isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC102101, AC158921
      Consensus CDS
      CCDS88733.1
      UniProtKB/TrEMBL
      A0A338P6B7
      Related
      ENSMUSP00000155921.2, ENSMUST00000167842.9
      Conserved Domains (2) summary
      sd00006
      Location:212 → 244
      TPR; TPR repeat [structural motif]
      pfam13424
      Location:248 → 317
      TPR_12; Tetratricopeptide repeat

    2. NM_001378877.1 → NP_001365806.1  tetratricopeptide repeat protein 23-like isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC102101, AC158921
      Conserved Domains (2) summary
      sd00006
      Location:236 → 268
      TPR; TPR repeat [structural motif]
      pfam13424
      Location:238 → 303
      TPR_12; Tetratricopeptide repeat

    3. NM_001378878.1 → NP_001365807.1  tetratricopeptide repeat protein 23-like isoform 4

      Status: VALIDATED

      Source sequence(s)
      AC158921
      Conserved Domains (2) summary
      sd00006
      Location:236 → 268
      TPR; TPR repeat [structural motif]
      pfam13424
      Location:238 → 303
      TPR_12; Tetratricopeptide repeat

    4. NM_029430.1 → NP_083706.1  tetratricopeptide repeat protein 23-like isoform 1

      See identical proteins and their annotated locations for NP_083706.1

      Status: VALIDATED

      Source sequence(s)
      AK015027, BC145852
      Consensus CDS
      CCDS49582.1
      UniProtKB/Swiss-Prot
      A3KMM7, A6H6E9, Q9D5Q3
      Related
      ENSMUSP00000022857.8, ENSMUST00000022857.14
      Conserved Domains (2) summary
      sd00006
      Location:212 → 244
      TPR; TPR repeat [structural motif]
      pfam13424
      Location:248 → 317
      TPR_12; Tetratricopeptide repeat

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000081.7 Reference GRCm39 C57BL/6J

      Range
      10497309..10559006 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030248814.2 → XP_030104674.1  tetratricopeptide repeat protein 23-like isoform X2

      Conserved Domains (2) summary
      sd00006
      Location:236 → 268
      TPR; TPR repeat [structural motif]
      pfam13424
      Location:238 → 303
      TPR_12; Tetratricopeptide repeat

    2. XM_017316786.3 → XP_017172275.1  tetratricopeptide repeat protein 23-like isoform X1

      Conserved Domains (2) summary
      sd00006
      Location:236 → 268
      TPR; TPR repeat [structural motif]
      pfam13424
      Location:272 → 341
      TPR_12; Tetratricopeptide repeat
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    A6H6E9.1 GenPept UniProtKB/Swiss-Prot:A6H6E9

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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