Tprg1 transformation related protein 63 regulated 1 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Tprg1provided by MGI
Official Full Name: transformation related protein 63 regulated 1provided by MGI
Primary source: MGI:MGI:1918588
See related: Ensembl:ENSMUSG00000048399 AllianceGenome:MGI:1918588
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Tprg; 5430420C16Rik
Summary: Located in cytoplasm. Is expressed in several structures, including gut; hemolymphoid system gland; liver; male reproductive gland or organ; and skin. Orthologous to human TPRG1 (tumor protein p63 regulated 1). [provided by Alliance of Genome Resources, Dec 2024]
Expression: Biased expression in stomach adult (RPKM 1.0), bladder adult (RPKM 0.4) and 4 other tissues See more
Orthologs: human all
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Genomic context

Location:: 16 B1; 16 17.0 cM

Exon count:: 7

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	16	NC_000082.7 (25105567..25242338)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	16	NC_000082.6 (25286817..25423588)

Chromosome 16 - NC_000082.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Tprg gene is predominantly expressed in skin, is physically associated with the p63 gene during evolution, and directly regulated by p63 through a long-distance enhancer located within the Tprg locus.
Title: Tprg, a gene predominantly expressed in skin, is a direct target of the transcription factor p63.
The Tprg gene is predominantly expressed in keratinocytes, is physically associated with the p63 gene during evolution, and is directly regulated by p63 through a long-distance enhancer located within the Tprg locus.
Title: Tprg, a gene predominantly expressed in skin, is a direct target of the transcription factor p63.

Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (1)

General gene information

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Markers

NoName (e-PCR)
- UniSTS:493211

Tprg (e-PCR), detects polymorphism
- UniSTS:526809

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	IDA Inferred from Direct Assay more info	PubMed

General protein information

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Preferred Names: tumor protein p63-regulated gene 1 protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.