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    Bcl11b B cell leukemia/lymphoma 11B [ Mus musculus (house mouse) ]

    Gene ID: 58208, updated on 9-Dec-2024

    Summary

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    Official Symbol
    Bcl11bprovided by MGI
    Official Full Name
    B cell leukemia/lymphoma 11Bprovided by MGI
    Primary source
    MGI:MGI:1929913
    See related
    Ensembl:ENSMUSG00000048251 AllianceGenome:MGI:1929913
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Rit1; Ctip2; BCL-11B; 9130430L19Rik; B630002E05Rik
    Summary
    Enables DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including T cell differentiation; epithelial cell development; and neuron differentiation. Located in neuron projection and nucleus. Part of SWI/SNF complex. Is expressed in several structures, including alimentary system; central nervous system; cranium; nose; and skin. Human ortholog(s) of this gene implicated in immunodeficiency 49. Orthologous to human BCL11B (BCL11 transcription factor B). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in thymus adult (RPKM 56.0), CNS E18 (RPKM 12.1) and 8 other tissues See more
    Orthologs
    human all
    NEW
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    Genomic context

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    See Bcl11b in Genome Data Viewer
    Location:
    12 F1; 12 59.1 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (107876662..107970404, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (107910403..108004145, complement)

    Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 4930465M20 gene Neighboring gene CapStarr-seq enhancer MGSCv37_chr12:108972876-108973059 Neighboring gene CapStarr-seq enhancer MGSCv37_chr12:109017655-109017838 Neighboring gene CapStarr-seq enhancer MGSCv37_chr12:109017971-109018080 Neighboring gene STARR-seq mESC enhancer starr_33225 Neighboring gene predicted gene, 33341 Neighboring gene STARR-seq mESC enhancer starr_33229 Neighboring gene CapStarr-seq enhancer MGSCv37_chr12:109157062-109157245 Neighboring gene CapStarr-seq enhancer MGSCv37_chr12:109164383-109164658 Neighboring gene CapStarr-seq enhancer MGSCv37_chr12:109166259-109166489 Neighboring gene STARR-seq mESC enhancer starr_33230 Neighboring gene CapStarr-seq enhancer MGSCv37_chr12:109202967-109203154 Neighboring gene CapStarr-seq enhancer MGSCv37_chr12:109231387-109231540 Neighboring gene STARR-seq mESC enhancer starr_33235 Neighboring gene SET domain containing 3 Neighboring gene STARR-positive B cell enhancer ABC_E743 Neighboring gene cyclin K Neighboring gene coiled-coil domain containing 85C Neighboring gene STARR-positive B cell enhancer mm9_chr12:109513689-109513989 Neighboring gene CapStarr-seq enhancer MGSCv37_chr12:109514813-109514922

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. BCL11B gene heterozygosity causes weight loss accompanied by increased energy consumption, but not defective adipogenesis, in mice. Inoue J, et al. Biosci Biotechnol Biochem, 2017 May. PMID 28067590
    2. Non-coding Transcription Instructs Chromatin Folding and Compartmentalization to Dictate Enhancer-Promoter Communication and T Cell Fate. Isoda T, et al. Cell, 2017 Sep 21. PMID 28938112, Free PMC Article
    3. Bcl11b prevents the intrathymic development of innate CD8 T cells in a cell intrinsic manner. Hirose S, et al. Int Immunol, 2015 Apr. PMID 25422283
    4. Selective ablation of Ctip2/Bcl11b in epidermal keratinocytes triggers atopic dermatitis-like skin inflammatory responses in adult mice. Wang Z, et al. PLoS One, 2012. PMID 23284675, Free PMC Article
    5. Kinetic analysis of BCL11B multisite phosphorylation-dephosphorylation and coupled sumoylation in primary thymocytes by multiple reaction monitoring mass spectroscopy. Vogel WK, et al. J Proteome Res, 2014 Dec 5. PMID 25423098, Free PMC Article

    See all (800) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. ARID1B maintains mesenchymal stem cell quiescence via inhibition of BCL11B-mediated non-canonical Activin signaling.
      Title: ARID1B maintains mesenchymal stem cell quiescence via inhibition of BCL11B-mediated non-canonical Activin signaling.
    2. Reactivation of corticogenesis-related transcriptional factors BCL11B and SATB2 after ischemic lesion of the adult mouse brain.
      Title: Reactivation of corticogenesis-related transcriptional factors BCL11B and SATB2 after ischemic lesion of the adult mouse brain.
    3. The Majority of the Serine/Threonine Phosphorylation Sites in Bcl11b Protein Are Dispensable for the Differentiation of T Cells.
      Title: The Majority of the Serine/Threonine Phosphorylation Sites in Bcl11b Protein Are Dispensable for the Differentiation of T Cells.
    4. Bcl11b sustains multipotency and restricts effector programs of intestinal-resident memory CD8[+] T cells.
      Title: Bcl11b sustains multipotency and restricts effector programs of intestinal-resident memory CD8(+) T cells.
    5. Symbiotic bacteria-dependent expansion of MR1-reactive T cells causes autoimmunity in the absence of Bcl11b.
      Title: Symbiotic bacteria-dependent expansion of MR1-reactive T cells causes autoimmunity in the absence of Bcl11b.
    6. Transcription factors Bcl11a and Bcl11b are required for the production and differentiation of cortical projection neurons.
      Title: Transcription factors Bcl11a and Bcl11b are required for the production and differentiation of cortical projection neurons.
    7. The transcription factor Bcl11b promotes both canonical and adaptive NK cell differentiation.
      Title: The transcription factor Bcl11b promotes both canonical and adaptive NK cell differentiation.
    8. Bcl11b is required for proper odorant receptor expression in the mouse septal organ.
      Title: Bcl11b is required for proper odorant receptor expression in the mouse septal organ.
    9. BCL11B Regulates Arterial Stiffness and Related Target Organ Damage.
      Title: BCL11B Regulates Arterial Stiffness and Related Target Organ Damage.
    10. Gut commensals suppress interleukin-2 production through microRNA-200/BCL11B and microRNA-200/ETS-1 axes in lamina propria leukocytes of murine large intestine.
      Title: Gut commensals suppress interleukin-2 production through microRNA-200/BCL11B and microRNA-200/ETS-1 axes in lamina propria leukocytes of murine large intestine.
    Submit: New GeneRIF Correction See all GeneRIFs (79)

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA-binding transcription activator activity, RNA polymerase II-specific IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables DNA-binding transcription factor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables sequence-specific DNA binding IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables sequence-specific double-stranded DNA binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of T cell apoptotic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within T cell differentiation in thymus IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within T cell receptor V(D)J recombination IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within alpha-beta T cell differentiation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of apoptotic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within axonogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within central nervous system neuron differentiation IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within commitment of neuronal cell to specific neuron type in forebrain IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within epithelial cell morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in hematopoietic stem cell migration ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in hematopoietic stem cell migration ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    acts_upstream_of_or_within keratinocyte development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in lymphoid lineage cell migration into thymus ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in lymphoid lineage cell migration into thymus ISS
    Inferred from Sequence or Structural Similarity
    more info
    		  
    acts_upstream_of_or_within negative regulation of T cell apoptotic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within negative regulation of cell population proliferation IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within negative regulation of thymocyte apoptotic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within odontogenesis of dentin-containing tooth IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within olfactory bulb axon guidance IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within positive T cell selection IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    involved_in positive regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within post-embryonic camera-type eye development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within post-embryonic development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of gene expression IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of keratinocyte proliferation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of lipid metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within regulation of neuron differentiation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within skin development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within striatal medium spiny neuron differentiation IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of thymocyte apoptotic process IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of_or_within thymus development IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    acts_upstream_of transcription by RNA polymerase II IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    acts_upstream_of transcription by RNA polymerase II IGI
    Inferred from Genetic Interaction
    more info
    		 PubMed 
    acts_upstream_of transcription by RNA polymerase II IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    part_of SWI/SNF complex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    part_of SWI/SNF complex ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in intracellular anatomical structure IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in neuron projection IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    B-cell lymphoma/leukemia 11B
    Names
    B-cell CLL/lymphoma 11B
    B-cell lymphoma/leukaemia 11B
    COUP-TF-interacting protein 2
    mRit1
    radiation-induced tumor suppressor gene 1 protein

    NCBI Reference Sequences (RefSeq)

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    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001079883.1 → NP_001073352.1  B-cell lymphoma/leukemia 11B isoform a

      See identical proteins and their annotated locations for NP_001073352.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longest isoform (a).
      Source sequence(s)
      AC119219, AC119921, BM950501, BQ442983, CV563304
      Consensus CDS
      CCDS36553.1
      UniProtKB/Swiss-Prot
      Q8C2I1, Q99PV6, Q99PV7, Q99PV8, Q9JLF8
      Related
      ENSMUSP00000068258.5, ENSMUST00000066060.11
      Conserved Domains (3) summary
      sd00017
      Location:788 → 808
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:787 → 808
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:800 → 825
      zf-H2C2_2; Zinc-finger double domain

    2. NM_001286343.1 → NP_001273272.1  B-cell lymphoma/leukemia 11B isoform c

      See identical proteins and their annotated locations for NP_001273272.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) lacks two internal coding exons but maintains the reading frame, compared to variant 1. The resulting isoform (c) lacks an internal segment, compared to isoform a.
      Source sequence(s)
      AC119219, AC119921
      Consensus CDS
      CCDS70419.1
      UniProtKB/TrEMBL
      A0A0R4J1E1
      Related
      ENSMUSP00000105513.2, ENSMUST00000109887.8
      Conserved Domains (3) summary
      sd00017
      Location:594 → 614
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:593 → 614
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:606 → 631
      zf-H2C2_2; Zinc-finger double domain

    3. NM_021399.2 → NP_067374.2  B-cell lymphoma/leukemia 11B isoform b

      See identical proteins and their annotated locations for NP_067374.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an in-frame coding exon, compared to variant 1. The resulting isoform (b) lacks an internal segment, compared to isoform a.
      Source sequence(s)
      AC119219, AC119921, BQ745012, CV563304
      Consensus CDS
      CCDS36552.1
      UniProtKB/Swiss-Prot
      Q99PV8
      Related
      ENSMUSP00000105517.3, ENSMUST00000109891.3
      Conserved Domains (4) summary
      sd00017
      Location:716 → 736
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:356 → 376
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:715 → 736
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:728 → 753
      zf-H2C2_2; Zinc-finger double domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000078.7 Reference GRCm39 C57BL/6J

      Range
      107876662..107970404 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006516111.4 → XP_006516174.1  B-cell lymphoma/leukemia 11B isoform X4

      Conserved Domains (4) summary
      sd00017
      Location:784 → 804
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:424 → 444
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:783 → 804
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:796 → 821
      zf-H2C2_2; Zinc-finger double domain

    2. XM_036157546.1 → XP_036013439.1  B-cell lymphoma/leukemia 11B isoform X5

      Conserved Domains (4) summary
      sd00017
      Location:783 → 803
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:423 → 443
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:782 → 803
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:795 → 820
      zf-H2C2_2; Zinc-finger double domain

    3. XM_011244153.3 → XP_011242455.1  B-cell lymphoma/leukemia 11B isoform X3

      Conserved Domains (4) summary
      sd00017
      Location:787 → 807
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:427 → 447
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:786 → 807
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:799 → 824
      zf-H2C2_2; Zinc-finger double domain

    4. XM_006516114.4 → XP_006516177.1  B-cell lymphoma/leukemia 11B isoform X9

      Conserved Domains (4) summary
      sd00017
      Location:715 → 735
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:355 → 375
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:714 → 735
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:727 → 752
      zf-H2C2_2; Zinc-finger double domain

    5. XM_017315145.3 → XP_017170634.1  B-cell lymphoma/leukemia 11B isoform X10

      Conserved Domains (4) summary
      sd00017
      Location:670 → 690
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:310 → 330
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:669 → 690
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:682 → 707
      zf-H2C2_2; Zinc-finger double domain

    6. XM_017315144.3 → XP_017170633.1  B-cell lymphoma/leukemia 11B isoform X10

      Conserved Domains (4) summary
      sd00017
      Location:670 → 690
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:310 → 330
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:669 → 690
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:682 → 707
      zf-H2C2_2; Zinc-finger double domain

    7. XM_036157548.1 → XP_036013441.1  B-cell lymphoma/leukemia 11B isoform X8

      Conserved Domains (4) summary
      sd00017
      Location:738 → 758
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:378 → 398
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:737 → 758
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:750 → 775
      zf-H2C2_2; Zinc-finger double domain

    8. XM_017315143.3 → XP_017170632.1  B-cell lymphoma/leukemia 11B isoform X7

      Conserved Domains (4) summary
      sd00017
      Location:742 → 762
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:382 → 402
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:741 → 762
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:754 → 779
      zf-H2C2_2; Zinc-finger double domain

    9. XM_006516110.5 → XP_006516173.1  B-cell lymphoma/leukemia 11B isoform X2

      Conserved Domains (4) summary
      sd00017
      Location:828 → 848
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:468 → 488
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:827 → 848
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:840 → 865
      zf-H2C2_2; Zinc-finger double domain

    10. XM_011244152.4 → XP_011242454.1  B-cell lymphoma/leukemia 11B isoform X1

      Conserved Domains (4) summary
      sd00017
      Location:832 → 852
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:472 → 492
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:831 → 852
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:844 → 869
      zf-H2C2_2; Zinc-finger double domain

    11. XM_006516113.5 → XP_006516176.1  B-cell lymphoma/leukemia 11B isoform X6

      Conserved Domains (4) summary
      sd00017
      Location:760 → 780
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:400 → 420
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:759 → 780
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:772 → 797
      zf-H2C2_2; Zinc-finger double domain

    12. XM_036157549.1 → XP_036013442.1  B-cell lymphoma/leukemia 11B isoform X8

      Conserved Domains (4) summary
      sd00017
      Location:738 → 758
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:378 → 398
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:737 → 758
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:750 → 775
      zf-H2C2_2; Zinc-finger double domain

    13. XM_036157547.1 → XP_036013440.1  B-cell lymphoma/leukemia 11B isoform X7

      Conserved Domains (4) summary
      sd00017
      Location:742 → 762
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:382 → 402
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:741 → 762
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:754 → 779
      zf-H2C2_2; Zinc-finger double domain

    14. XM_006516116.4 → XP_006516179.1  B-cell lymphoma/leukemia 11B isoform X12

      Conserved Domains (4) summary
      sd00017
      Location:608 → 628
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:248 → 268
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:607 → 628
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:620 → 645
      zf-H2C2_2; Zinc-finger double domain

    15. XM_006516115.4 → XP_006516178.1  B-cell lymphoma/leukemia 11B isoform X11

      Conserved Domains (4) summary
      sd00017
      Location:657 → 677
      ZF_C2H2; C2H2 Zn finger [structural motif]
      sd00019
      Location:297 → 317
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:656 → 677
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:669 → 694
      zf-H2C2_2; Zinc-finger double domain
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q99PV8.1 GenPept UniProtKB/Swiss-Prot:Q99PV8

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