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    LRGUK leucine rich repeats and guanylate kinase domain containing [ Trichechus manatus latirostris (Florida manatee) ]

    Gene ID: 101359481, updated on 8-Mar-2024

    Summary

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    Gene symbol
    LRGUK
    Gene description
    leucine rich repeats and guanylate kinase domain containing
    Gene type
    protein coding
    RefSeq status
    MODEL
    Organism
    Trichechus manatus latirostris (sub-species: latirostris)
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Afrotheria; Sirenia; Trichechidae; Trichechus
    Orthologs
    human mouse all
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    Genomic context

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    See LRGUK in Genome Data Viewer
    Location:
    chromosome: Un
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    RS_2024_01 current TriManLat1.0 (GCF_000243295.1) Unplaced Scaffold NW_004444033.1 (8719695..8855279)

    NW_004444033.1Genomic Context describing neighboring genes Neighboring gene coiled-coil-helix-coiled-coil-helix domain containing 3 Neighboring gene uncharacterized LOC111821683 Neighboring gene exocyst complex component 4 Neighboring gene transfer RNA glutamic acid (anticodon UUC) Neighboring gene solute carrier family 35 member B4 Neighboring gene BLOC-1-related complex subunit 7 pseudogene

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NW_004444033 Unplaced Scaffold Reference TriManLat1.0 Primary Assembly

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
    2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables guanylate kinase activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytosol IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    leucine-rich repeat and guanylate kinase domain-containing protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs of Annotated Genomes: GCF_000243295.1-RS_2024_01

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference TriManLat1.0 Primary Assembly

    Genomic

    1. NW_004444033.1 Reference TriManLat1.0 Primary Assembly

      Range
      8719695..8855279
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_023737149.1 → XP_023592917.1  leucine-rich repeat and guanylate kinase domain-containing protein

      UniProtKB/TrEMBL
      A0A2Y9RER7
      Conserved Domains (3) summary
      COG4886
      Location:143 → 331
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      cd00071
      Location:427 → 603
      GMPK; Guanosine monophosphate kinase (GMPK, EC 2.7.4.8), also known as guanylate kinase (GKase), catalyzes the reversible phosphoryl transfer from adenosine triphosphate (ATP) to guanosine monophosphate (GMP) to yield adenosine diphosphate (ADP) and guanosine ...
      sd00033
      Location:142 → 161
      LRR_RI; leucine-rich repeat [structural motif]
    Nucleotide Protein
    Heading Accession and Version

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