Ldoc1 regulator of NFKB signaling [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Ldoc1provided by MGI
Official Full Name: regulator of NFKB signalingprovided by MGI
Primary source: MGI:MGI:2685212
See related: Ensembl:ENSMUSG00000057615 AllianceGenome:MGI:2685212
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Mar7; Rtl7; Gm366; Mart7; Sirh7
Summary: Acts upstream of or within maternal placenta development; maternal process involved in parturition; and regulation of growth hormone activity. Predicted to be located in nucleolus and nucleoplasm. Is expressed in brain and ovary. Orthologous to human LDOC1 (LDOC1 regulator of NFKB signaling). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs: human all
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Genomic context

Location:: X A6; X 34.57 cM

Exon count:: 1

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	X	NC_000086.8 (60753217..60754556)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	X	NC_000086.7 (61709611..61710950)

Chromosome X - NC_000086.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (2)
Targeted (1) 1 citation

General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in cellular response to lipopolysaccharide	ISO Inferred from Sequence Orthology more info
involved_in cellular response to lipopolysaccharide	ISS Inferred from Sequence or Structural Similarity more info
involved_in cellular response to muramyl dipeptide	ISO Inferred from Sequence Orthology more info
involved_in cellular response to muramyl dipeptide	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within maternal placenta development	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within maternal process involved in parturition	IMP Inferred from Mutant Phenotype more info	PubMed
acts_upstream_of_or_within regulation of growth hormone activity	IMP Inferred from Mutant Phenotype more info	PubMed

Component	Evidence Code	Pubs
located_in nucleolus	IEA Inferred from Electronic Annotation more info
located_in nucleolus	ISO Inferred from Sequence Orthology more info
located_in nucleoplasm	IEA Inferred from Electronic Annotation more info
located_in nucleoplasm	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: protein LDOC1

Names: breast cancer, up-regulated 1; leucine zipper, down-regulated in cancer 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.